He adds that the zinc finger nucleases could have unpredictable effects on several genes.
他还补充说锌指核酸酶可能对一些基因具有不可预知的作用。
Zinc fingers are usually attached to enzymes called nucleases, dubbed ZFNs, which cut both strands of DNA.
通常附着在核酸酶上的锌指，称作ZFNs，它负责切断dna的两条链。
Unlike nucleases, recombinases cut a double-stranded piece of DNA and then wait around on the exposed ends.
重组酶与核酸酶不同，它剪断基因的双链，然后在断点的周围等候。
The research of artificial nucleases is of importance from the standpoint of biology, chemistry and medicine.
无论从生物学、化学和医学的角度，人工核酸酶的研究都具有非常重要的理论及应用价值。
They designed nucleases to home in on a tobacco gene that controls the plant's susceptibility to certain herbicides.
他们设计将核酸酶导入到控制植物对特定除草剂敏感的烟草基因中。
Clinical trials are underway in HIV patients of zinc-finger nucleases that remove a gene that allows the virus to enter immune cells.
目前正对HIV感染者进行锌指核酸酶临床实验，利用这种酶删除一段使病毒进入免疫细胞的基因。
When they exposed tobacco cells to the zinc finger nucleases, they also added a version of that gene that enhances herbicide resistance.
他们在使烟草细胞接触锌指核酸酶之外，也添加了可增强抗除草剂特性的基因片段。
Design, synthesis, and catalytic performance of artificial nucleases is full of challenging and has received intensive study in chemistry.
人工核酸酶的设计合成与性能研究是化学领域富有挑战性的热门研究方向之一。
Some investigators consider the agent to consist only of protein because its infectious nature is destroyed by proteases but not by nucleases.
一些研究者认为病原体仅仅由蛋白质组成，因为它的传染性能被蛋白酶而不是核酸酶所破坏。
Nano-delivery system increases cellular uptake of specific gene, protects them against nucleases and enhances their targeting and selectivity.
纳米控释系统使转染基因的胞内摄入量增高，增强其稳定性、靶向性及细胞定位。
The enzymes — known as zinc finger nucleases — can be engineered in the lab to target specific genes, introducing changes known to cause the desired trait.
这些酶名为锌脂蛋白核算酶，可在实验室内加工后靶向作用于特定基因，引入序列改变，获得希望得到的特性。
First, we can understand the catalysis mechanism and the role of the metal in it through studying the transition metal complex as the model of natural nucleases;
首先过渡金属配合物作为许多天然核酸酶的模型通过对其研究我们可以了解天然酶的催化机理及金属离子的作用；
Zinc finger nucleases (ZFNs) are artificial restriction enzymes made by fusing an engineered zinc finger DNA-binding domain to the DNA cleavage domain of a restriction enzyme.
锌指核酸酶是一种人工制做限制性内切酶，通过将锌指DNA结合区与限制性内切酶的DNA切割区融合获得。
Zinc-finger nucleases are enzymes that can be designed to find specific DNA sequences in the genome and cut them out, deleting those sequences or swapping one gene for another.
锌指核酸酶被设计识别基因组特定DNA序列，之后对其进行酶切，进而删除或替换这段序列。
The fourth section reports a series of new ligands and their many different metal functional coordination compounds as artificial nucleases were designed and synthesized by author.
第四部分是报导我们设计和合成了作为人工核酸酶的一系列新的配体以及许多不同金属的功能配合物；
There is a growing interest in the field of polyazamacrocyles as excellent artificial nucleases, due to their ability to form chelates in aqueous solutions and to coordinate with most metal cations.
由于大环多胺能与很多金属在水溶液里形成配合物而作为人工核酸酶，引起了人们的广泛关注。
There is a growing interest in the field of polyazamacrocyles as excellent artificial nucleases, due to their ability to form chelates in aqueous solutions and to coordinate with most metal cations.
由于大环多胺能与很多金属在水溶液里形成配合物而作为人工核酸酶，引起了人们的广泛关注。
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