The researchers hope this discovery will lead to drugs that target NR2B specifically.
研究者们希望这个发现能有助于针对NR2B基因的药物研发。
The tyrosine phosphorylation of NR2B was analyzed by immunoprecipitation and immunoblot assay.
NR2B酪氨酸磷酸化通过免疫沉淀和免疫印渍分析。
NR2B subunits which are highly expressed in the cortex, hippocampus and olfactory bulb, are one of the key subunits of NMDA receptors.
其中NR2B是NMDA受体的主要亚基之一，在大脑皮层、海马和嗅球表达水平很高。
By increasing "pore" activity with the over-expressed NR2B gene, the scientists effectively increased processing speed of the rat's brain.
科学家们通过增加小孔的活动，有效的提高了老鼠大脑的运转速度。
Diseases like Alzheimer's affect NR2B expression, so a drug that causes the gene to over-express could counteract the affects of the disease.
像老年痴呆症这样的疾病会影响NR2B的表达，而可以使该基因过表达的药物能够抵消这些疾病的影响。
Accumulating evidence indicates that, NR2B is crucial for synaptic plasticity, learning and memory and nervous system degenerative diseases.
大量实验数据证明，NR2B亚单位与哺乳动物的突触可塑性、学习记忆、痛觉和神经系统疾病有关。
We use this device for multi-channel recording in CA1 area of rat. It allows us to study the in vivo neurons activities of NR2B transgenic rat.
并使用该装置在NR2B转基因大鼠海马脑区开展了多通道在体记录的相关研究，考察NR2B转基因大鼠海马神经元的在体电活动。
Results Compared with control group, the learning and memory ability of model group obviously damaged and the expression of NR2B in hippocampus decreased (all P<0.05).
结果与对照组相比，模型组大鼠学习、记忆功能明显下降，海马NR2B表达明显降低（均P<0.05）；
Conclusion: NR2B is essential for the formation of long term memory, reconsolidation of Y-maze memory. The deactivation of NR2B by ifenprodil will impair these courses.
结论：NR2B对于大鼠y迷宫长期记忆的形成、记忆再巩固过程是必要的，NR2B的失活将破坏这些过程。
So it was supposed that NR2B subunit played an important role in experience-dependent developmental plasticity and changes in NR2B expression would affect developmental plasticity.
据测NR2B亚单位与经验依赖性的发育可塑性密切相关，改变特定脑区NR2B亚单位的表达，可以影响相应系统的发育可塑性。
The presence of NR2B plays the most important function among these subunits, NR2B has been utilized to modulate learning and memory, synaptic plasticity, and treating mental disorders.
近年来对NR2B研究表明，其在调控神经元突触的可塑性、学习与记忆以及治疗精神紊乱方面具有重要的意义。
The results indicated that, auditory deprivation and experience can modify the protein expression level of NMDA receptor subunit NR2B during the critical period of rat postnatal development.
结果提示，在大鼠生后发育关键期，听觉剥夺、经验可改变听皮层NMDA受体NR2B蛋白表达水平。
AIM: To study the effects of chronic multiple stress on learning and memory and changes of N-methyl-D-asparagic acid (NMDA) receptor subunits NR2A and NR2B expression in hippocampus of rats.
目的：观察慢性复合应激对大鼠学习与记忆的影响及应激后脑海马内N-甲基-D-天冬氨酸受体亚基NR2A，NR2B表达的变化。
AIM: To study the effects of chronic multiple stress on learning and memory and changes of N-methyl-D-asparagic acid (NMDA) receptor subunits NR2A and NR2B expression in hippocampus of rats.
目的：观察慢性复合应激对大鼠学习与记忆的影响及应激后脑海马内N-甲基-D-天冬氨酸受体亚基NR2A，NR2B表达的变化。
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