The chemical modification of sugar moiety in nucleoside or nucleotide is always an important way to discover new lead compounds with anti-viral, anti-tumor and other biological activities.
对核苷类化合物糖环部分的化学改造一直是发现新的具有抗病毒、抗肿瘤或其他生物活性的核苷类先导化合物的重要途径之一。
In this paper, according to the principles of new drug design, On the basis of former research the 10 compounds guided by the lead compound PHR0007 were synthesized.
本文在前人研究的基础上,以PHR0007为先导化合物,按着新药设计原理合成了10个未见文献报道的化合物。
The invention can provide lead compounds for the development of new anti-cancer drugs and is expected to become the drugs for cancer treatment.
本发明可为研制新的抗肿瘤药物提供先导化合物,可望成为治疗癌症的药物。
The invention can provide lead compounds for the development of new anti-cancer drugs and is expected to become the drugs for cancer treatment.
本发明可为研制新的抗肿瘤药物提供先导化合物,可望成为治疗癌症的药物。
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