The actin filament-binding protein, Afadin, binds to nectin forming a connection to the actin cytoskeleton (3).
肌动蛋白丝结合蛋白,Afadin,和nectin结合后形成一个连接与肌动蛋白丝细胞骨架连接(3)。
AJs are formed when nectin assembles cadherin at the cell-cell adhesion site and these junctions are then involved in the formation and maintenance of TJs (4, 5).
当nectin募集钙粘蛋白到细胞-细胞黏附位置时会形成AJs,这些连接随后会涉及到TJs的形成和维持(4,5)。
AJs are formed when nectin assembles cadherin at the cell-cell adhesion site and these junctions are then involved in the formation and maintenance of TJs (4, 5).
当nectin募集钙粘蛋白到细胞-细胞黏附位置时会形成AJs,这些连接随后会涉及到TJs的形成和维持(4,5)。
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