Lac-NCTD was synthesized with ethanediamine as truss arm.
利用乙二胺为连接臂合成乳糖化-去甲斑蝥素修饰物。
METHODS Lac-NCTD was synthesized with ethanediamine as truss arm, and then its properties were studied.
方法利用乙二胺为连接臂合成乳糖化-去甲斑蝥素修饰物，并考察其相关理化性质；
Results: NCTD significantly reduced tissue invasion around tumor cells and lung metastasis compared with control (P<0.05).
结果：在动物实验中，NCTD可明显减少荷瘤裸鼠移植瘤的瘤周组织浸润和肺转移瘤结节（P＜0.05）；
The drug loading rate, encapsulation efficiency, particle distribution and in vitro release of Lac-NCTD from liposomes were investigated, respectively.
考察了药物与磷脂的复合率，磷脂复合物脂质体的包封率，粒径大小和分布，以及体外释药特性。
Methods: Lac-NCTD phospholipid complex was prepared using solvent-evaporation, and its correlated physicochemical properties were confirmed with solubility test, FT-IR, DSC and 1H-NMR.
方法：将乳糖化-去甲斑蝥素与磷脂聚合成药物磷脂复合物，并采用FT-IR、DSC和1H-NMR对其进行表征。
Methods: Lac-NCTD phospholipid complex was prepared using solvent-evaporation, and its correlated physicochemical properties were confirmed with solubility test, FT-IR, DSC and 1H-NMR.
方法：将乳糖化-去甲斑蝥素与磷脂聚合成药物磷脂复合物，并采用FT-IR、DSC和1H-NMR对其进行表征。
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