Because the normal allele (a) can completely cancel the mutant allele (a), animals with Aa or Aa look the same.
因为正常等位基因(A)可以完全取消突变等位基因(一),动物使用AA或AA看起来是一样的。
The latter reflects the selective constraints on the probabilities of fixation of a mutant allele in genome type.
后者反映了选择约束对密码子分布的影响。
Tumor cellularity and mutant allele frequency were analyzed to identify tumor heterogeneity and mutant allele-specific imbalance.
通过分析肿瘤细胞的密度及等位基因突变的几率来确定肿瘤异质性和等位基因特异性突变的不平衡性。
The paper reporting the study states: "Nine subjects from a cohort of 87 depression patients were found to carry the mutant allele.
研究报告写道:“在87名抑郁症病人中有9名受试者被发现些带有变异的等位基因。
Obligate heterozygote --- An individual who may be clinically unaffected but on the basis of pedigree analysis must carry a specific mutant allele.
遗传上已确认为携带特异的突变等位基因,但临床上还未发病的个体。
Next-generation sequencing showed precise measurement of mutant allele frequencies and detected 23% of mutations with 2-20% mutant allele frequencies.
新一代测序技术对等位基因特异性突变几率非常精确,检测出了23%的基因突变、其中等位基因突变的几率达2- 20%。
Genetic lethal --- A mutant allele or genetically determined trait that leads to failure to reproduce, although not necessarily to death prior to reproduction.
不同基因型决定相同表型的现象。参见等位基因异质性、临床异质性和基因座异质性。
Lower than expected mutant allele frequency indicated tumor heterogeneity, while higher than expected mutant allele frequency indicated mutant allele-specific imbalance.
等位基因突变几率预测肿瘤异质性方面低于预期,但等位基因突变几率预测等位基因特异性突变不平衡性方面则高于预期。
The repressor gene and its allele-a temperature sensitive mutant have been cloned from the defective prophage PBSX of Bacillus subtilis by means of PCR technique.
本研究利用聚合酶链式反应技术,成功地克隆了枯草芽孢杆菌缺陷型原噬菌体PBSX阻遏基因及其温度敏感型等位基因。
The repressor gene and its allele-a temperature sensitive mutant have been cloned from the defective prophage PBSX of Bacillus subtilis by means of PCR technique.
本研究利用聚合酶链式反应技术,成功地克隆了枯草芽孢杆菌缺陷型原噬菌体PBSX阻遏基因及其温度敏感型等位基因。
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