Objective To investigate the changes in CREB-1 protein expression in three brain regions induced by acute or chronic morphine dependence and withdrawal.
目的研究急性或慢性吗啡依赖和戒断大鼠脑组织环腺苷酸反应元件结合蛋白-1 （CREB-1）表达的变化。
ObjectiveTo investigate the effect of NMDA receptor antagonist MK801 on the negative affection induced by withdrawal from acute morphine dependence in rats.
目的谷氨酸NMDA受体拮抗剂地卓西平（MK801）对大鼠急性吗啡依赖戒断性情绪反应的影响。
Conclusion morphine may affect purine nucleotide metabolism of nerve cells, increase the adenylate and adenosine levels, which may be one of the mechanism of morphine dependence and tolerance.
结论：吗啡影响神经细胞嘌呤核苷酸代谢，使细胞内腺苷酸及腺苷水平增高，这可能是吗啡依赖和耐受形成的机理之一。
Methods: The anxiety mice model was formed based on the principle of morphine increase progressively day by day, in which after the mice were induced into morphine dependence, naloxone was given.
方法：按照逐日递增原则给予小鼠皮下注射吗啡，以纳洛酮催瘾，建立吗啡戒断后焦虑动物模型。
High living, including a dependence on painkillers like morphine, helped bring her a bleeding ulcer and liver damage; more than once she collapsed dramatically onstage.
高压的生活再加上对吗啡等止痛药物的依赖，导致她患上了出血性胃溃疡和肝损害。
Morphine physical dependence was induced on day 10 in SD rats by daily administration of morphine sulphate(MS), but not morphine hydrochloride(MH), in their drinking water.
在饮水中溶入硫酸吗啡，逐日提高吗啡浓度，SD大鼠在饮入吗啡后第10天产生明显的吗啡依赖。而同样方法饮入盐酸吗啡效果较差。
Mouse dependence model was established by drinking increasing concentrations of morphine( Mor) in tap water, with which several parameters of immune function were evaluated.
以饮用吗啡药水法建立小鼠依赖模型，探讨其免疫机能的改变。
METHODS: According to evaluation index of dependence in Morphine addicted animals, we chose pain threshold and naloxone urged jumping response as items to observe.
方法：依据吗啡成瘾动物的依赖性评价指标，选择痛阈和纳络酮跳台反应作为观察项目。
Nitric oxide, an intracellular messenger molecule linked to activation of N Methyl D aspartate(NMDA) receptor, plays a role in morphine tolerance and dependence.
一氧化氮（NO）是与N甲基D 天（门）冬氨酸（NM DA）受体活性相关的一种细胞内信使分子，在吗啡耐受和依赖中起作用。
Objective: to observe the ultrastructure and synaptic number of cerebral regions related to psychological dependence in rats with different morphine dependent time.
目的：观察不同时程吗啡依赖大鼠心理依赖相关脑区超微结构和突触数量的变化。
Objective:Using the outer-cell recording to observe the morphine responses of nucleus accumbens and ventral subiculum, and explore the function of them in the process of drug-dependence.
目的：用胞外记录的方法分别观察伏隔核和海马腹侧下托对吗啡的反应性，探讨其在药物心理依赖形成过程中所处的地位。
Perceptual training could speed up recovering the cognition, we assume the mechanism is that perceptual training can adjust the neuroplasticity of dependence on morphine again.
视知觉学习训练似乎可以促进认知功能康复的进程，其机理可能是视知觉学习训练重新调整了吗啡依赖的神经可塑性。
Objective: To study the withdrawal effect of alkaloid on the morphine-dependence Animals.
目的：探讨一种可食用植物提取物———生物碱对成瘾动物依赖性的戒断作用。
Objective: To study the withdrawal effect of alkaloid on the morphine-dependence Animals.
目的：探讨一种可食用植物提取物———生物碱对成瘾动物依赖性的戒断作用。
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