The objective is to observe the expression of MMP-1and TIMP-1 in nucleus pulposus cells of intervertebral disc degeneration.
目的是测定 MMP-1及TIMP-1在人退变椎间盘髓核中的表达。
Rabbit matrix metalloproteinase 1, MMP-1 Elisa…
兔基质金属蛋白酶1（MMP-1）试剂盒；
Results There was no significant correlation between MMP-1 and BMD as well as bone turnover biochemical markers.
结果MMP-1与骨密度及骨转换生化指标无明显相关性；
Objective To observe tile effects of MMP-1 (Matrix Metalloproteinase-1) expressing plasmid on rat liver fibrosis.
目的观察间质胶原酶(MMP - 1)表达质粒对大鼠肝纤维化的影响。
The MMP-1 positive cells were found in all strata of cholesteatoma epithelium and active multiplication stromal cell.
MMP-1蛋白产物表达于胆脂瘤上皮细胞全层、增殖活跃的基底细胞及淋巴细胞散在表达。
Results (1) There were no significant negative relationships between MMP-1, TIMP-1 and BMD and bone biochemical markers.
结果（1）绝经后妇女血清MMP-1、TIMP-1水平与骨密度、骨转换生化指标无明显相关性。
Observing the changes of cornea by fluorescence sodium dyeing simultaneously. ResultsNo MMP-1 and its inhibitor's expression were found in the normal rat cornea.
同期采用荧光素钠染色，于裂隙灯下观察角膜形态学的变化。
By analyzed with immunohistochemistry in 45 HCCs, the MMP-1 expression in HCCs with invasion or metastasis is higher than that without invasion and metastasis (P0.05).
在45例肝癌组织中，应用免疫组织化学分析显示，高侵袭组MMP - 1表达明显高于低侵袭组(P 0.05)。
Conclusion Rosiglitazone can adjust the mRNA expressions of MMP-1 and TIMP-1 and inhibit the cumulation of extracellular matrix in kidney fibroblasts induced by high glucose.
结论罗格列酮可以通过调节MMP - 1和TIMP - 1的基因表达，抑制高糖导致的肾脏成纤维细胞外基质的蓄积。
Objective: to study the mechanism of YI-FEI-KANG-XIN capsule in patients with chronic pulmonary heart disease and to explore the effect of the serum level of matrix metalloproteinase-1 (MMP-1).
目的：观察临床经验方益肺康心胶囊对慢性肺源性心脏病的治疗效果，及其对患者血清中基质金属蛋白酶- 1的影响。
Objective To study the significance of expression of Matrix Metalloproteinase-1(MMP-1) , Tissue Inhibitor of Metalloproteinase-1(TIMP-1) and Proliferating cell nuclear antigen (PCNA) in abnormal scar.
目的：研究基质金属蛋白酶-1（MMP-1）、金属蛋白酶组织抑制剂-1（TIMP-1）、增殖细胞核抗原（PCNA）在病理性瘢痕中的表达及意义。
Results : ( 1 ) The positive expression of MMP - 2 reinforces gradually from normal villus, benign mole to malignant mole which has statistically significance ( P < 0. 05 ).
结果（1）从正常绒毛→良性葡萄胎→恶性葡萄胎，MMP-2的阳性率有升高趋势，差异有统计学意义（P〈0.05）。
Conclusion MMP-2, MMP-9 and TIMP-1 play an important role in the infiltrative metastasis of seminoma and may act as one of the factors to evaluate prognosis.
结论MMP - 2、MMP - 9、TIMP - 1在人睾丸精原细胞瘤的浸润转移过程中起重要作用，有可能成为估计预后的指标之一。
Endothelial dysfunction can be measured by the increased levels of a set of biomarkers, such as serum endothelin-1, E-Selectin and MMP-9.
血管内皮功能障碍可以通过一系列生物标志物：血清内皮素- 1,e -选择素和mmp—9水平的提高来评估。
The biomarkers of endothelial dysfunction, serum endothelin-1, E-Selectin and MMP-9, levels were also lower for the patients taking vitamin d.
服用维生素d的患者，内皮功能障碍的生物标志物如：血清内皮素1、E -选择和MMP - 9，水平也较低。
Methods the recent literatures on MMP 1 in skin wound repair were reviewed, which gave the insight into the local effect of MMP 1 during re epithelialization.
方法回顾近年来有关MMP - 1在皮肤损伤修复中的作用及研究进展，总结其在上皮化局部微小环境内的表达及细胞分子生物学效应。
Objective to study the expression of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) proteins in the decidua and villi of the early pregnancy.
目的研究基质金属蛋白酶- 9 (MMP - 9)和基质金属蛋白酶抑制物- 1 (TIMP - 1)在早孕期蜕膜和绒毛中的表达特点。
To evaluate significance of serum levels of MMP-9 and TIMP-1 as serum target of plaque rupture.
评价血清mmp 9及TIMP 1水平作为粥样斑块破裂的血清学指标的意义。
AIM: To determine the distribution of matrix metalloproteinase (MMP) -1 in the gingiva of chronic periodontitis and investigate the role of it in the pathogenesis of chronic periodontitis.
目的：通过检测基质金属蛋白酶- 1 (MMP - 1)在慢性牙周炎牙龈组织中的表达和分布特征，探讨MMP - 1在慢性牙周炎发病中的作用和临床意义。
Objective To investigate the expression of membrane type-1 matrix metalloproteinase(MT1-MMP) in human glioma and its relationship to clinicopathological factors and prognosis of glioma patients.
目的探讨膜型基质金属蛋白酶-1在人脑胶质瘤中的表达及其与肿瘤生物学行为和预后的关系。
Methods a rat model of cerebral aneurysm was established. The dynamic changes of MMP-2, MMP-9 and TIMP-1 expression were examined in the process of aneurysm formation.
方法制作肾性高血压大鼠脑动脉瘤模型，系统动态观察脑动脉瘤形成过程中MMP - 2、MMP - 9及其特异性抑制物(TIMP - 1)表达的变化。
Conclusions The abnormal expressions of MMP? 1, 2, 3 and TIMP? 1, 2, which resulted in degradation disorder of extracellular matrix, could induce degeneration of cartilage.
结论在骨关节炎中MMP 1、2、3和TIMP 1、2表达异常，引起细胞外基质异常降解，是导致关节软骨发生组织学退变的原因之一。
Objective To investigate the relationship between the ratio of MMP-3 to TIMP-1 and articular cartilage injury after ischemia-reperfusion.
目的探讨缺血再灌注后关节软骨中MMP - 3/TIMP - 1比例变化与软骨损伤的关系。
Immunohistochemical streptavidin-peroxidase (S-P) method was used to detect the expression of MMP-9, TIMP-1, in 15 cases with partial hydatidiform moles and 55 cases with complete hydatidiform mole.
应用链霉菌抗生物素蛋白—过氧化物酶免疫组织化学方法检测15例部分性葡萄胎、55例完全性葡萄胎滋养细胞中MMP-9、TIMP-1表达。
The interaction between ET-1 and MMP-9, both of which enhanced in damaged HBECs, may play an important role in airway inflammation related to airway remodeling in asthma.
结论：ET - 1与MMP - 9的相互影响在介导哮喘气道炎症与组织重塑的联系中起着重要的作用。
Objective: To study the expression of matrix metalloproteinases-9(MMP-9) and tissue inhibitor of metalloproteinases-1(TIMP-1) in placenta from patients with severe pregnancy induced hypertension(PIH).
目的：探讨基质金属蛋白酶9（MMP-9）、金属蛋白酶组织抑制因子1（TIMP-1）在正常妊娠和重度妊娠高血压综合征患者胎盘组织中的表达及其意义。
ConclusionThe expression of MMP-2, TIMP-1 and TIMP-2 are closely correlated with the development of the invasive activity of human astrocytoma.
结论MMP - 2、TIMP - 1和TIMP - 2在星形细胞肿瘤组织中的表达与星形细胞肿瘤的侵袭性生物学行为的演进密切相关。
There was significant difference in serum level of MMP-9 and TIMP-1 between ACS, SAP, and control group.
SAP组血清mmp 9水平高于正常对照组，而血清TIMP 1水平低于正常对照组，也具有统计学意义。
Methods Using New Zealand Rabbits, carotid atherosclerotic stenosis (CASS) model were created. The expression of ICAM-1 and MMP-2 of neointima after CEA were detected by immunohistochemical technique.
方法以新西兰兔颈动脉粥样硬化性狭窄动物模型为基础，采用免疫组织化学的方法检测颈动脉内膜切除术后不同时间点新内膜中ICAM - 1、MMP - 2基因的表达。
Results: Hydrosalpinx fluid significantly decreased the hatching rate of blastocysts and the concentrations of MMP-9 and TIMP-1 both in blastocysts and culture medium, in a dose dependent manner.
结果输卵管积液组的囊胚孵出率低于无积液组，囊胚及培养液中的MMP-9和TIMP-1低于无积液组，并呈剂量依赖性，MMP-9/TIMP-1随积液浓度增加而降低。
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