Protein state prior to misfolding.
错误折叠之前的蛋白质状态。
Our goal: to understand protein folding, misfolding, and related diseases.
项目目标：了解蛋白质折叠、误折以及相关的疾病。
Could the damaging events of protein misfolding be prevented or at least delayed?
这些蛋白错误折叠的损伤时间能被阻止或者最大限度的延迟吗？
One of its main actions is to recognize misfolded or unfolded proteins and then correct the misfolding or unfolding.
其主要作用之一就是识别错误折叠或未折叠蛋白质，并继而纠正这种错误折叠或未折叠。
In recent years, a number of diseases are believed to be caused by amyloid deposition results from protein misfolding.
近年来研究发现，蛋白质的错误折叠可以形成淀粉样沉积进而导致一些疾病的产生。
Dr Drayna suspects that both conditions are caused by misfolding of the enzymes in question, but that the details are different.
德雷纳博士怀疑这两种病状都是由错误折叠酶引起，但细节有所不同。
And chemicals that seem either to prevent the misfolding, or to help the body clear away misfolded molecules, do, indeed, exist.
能阻止分子错误折叠或帮助机体清除错误折叠分子的化学药品似乎确实存在。
The video from which Figure 1 was captured is a visualization of part of a sequence of a lysozyme protein misfolding due to a single mutation.
图1的来源视频呈现了由于单一突变造成的溶解酵素蛋白质的序列的一部分。
CJD and a handful of similar neurological conditions are caused by the misfolding of a particular protein that is found in the membranes of certain nerve cells.
该病以及类似的一些神经症状是由于某种神经细胞的细胞膜上的一个特殊蛋白发生错误折叠所致。
The Blue Gene/L technology offers a powerful way to study these types of diseases, because it provides a more cost-effective (and faster) way to model the effects of protein folding and misfolding.
BlueGene/L技术提供了一种强大的方法来研究这些类型的疾病，因为它能够更加经济高效地（和更快地）建模蛋白质折叠和错误折叠的效果。
The Blue Gene/L technology offers a powerful way to study these types of diseases, because it provides a more cost-effective (and faster) way to model the effects of protein folding and misfolding.
BlueGene/L技术提供了一种强大的方法来研究这些类型的疾病，因为它能够更加经济高效地（和更快地）建模蛋白质折叠和错误折叠的效果。
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