• MiRBase (Release 12.0), the central database for miRNAs, lists over 8 000 miRNAs from plants, animals and viruses.

    microRNA的中心文库——miRBase (Release 12.0)包含了超过8000种植物、动物和病毒的microRNA。

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  • While some of these miRNAs were in common with ones found in lung cancer sera, there were 10 miRNAs specific to just lung or colorectal cancers.

    虽然一些microRNA在肺癌和结肠癌患者的血清中同时发现,但有10种microRNA是肺癌和结肠癌各自特异的。

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  • Tumor miRNAs may be present as a result of tumor cells dying and getting lysed or tumor cells releasing miRNAs into the surrounding environment.

    肿瘤microRNA在血液中的存在可能是肿瘤死亡和溶解,或者由肿瘤细胞释放出microRNA到其周围微环境的结果。

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  • MiRNAs are very stable in blood plasma and serum: they are well protected from RNases and remain stable after being subjected to harsh conditions 2, 4.

    microRNA在血浆和血清中非常稳定,它们被有效保护以免接触RNases,在严酷环境的条件下仍能保持稳定。

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  • More recent research has shown that miRNAs also play an important role in cancer.

    最近的研究已经表明miRNA也在癌症中发挥重要作用。

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  • OBJECTIVE: To define the expression pattern of miRNAs in pancreatic cancer and compare it with those of normal pancreas and chronic pancreatitis.

    目的:了解胰腺癌微rna表达模式,并与正常胰腺和慢性胰腺炎比较。

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  • RNA interference through non-coding microRNAs (miRNAs) represents a vital component of the innate antiviral immune response in plants and invertebrate animals;

    借助非编码的微小RNA发挥的RNA干扰作用是植物和无脊椎动物先天抗病毒免疫反应的关键组成部分。

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  • Therefore, our findings strongly support the notion that mammalian organisms too, through the interferon system, use cellular miRNAs to combat viral infections.

    因此,我们的发现有力地支持了哺乳动物也通过干扰素系统,利用细胞内微rna来抵抗病毒感染这一观点。

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  • It identified about 100 different miRNAs that are present usually at very high levels in the tumor tissue compared with their levels in normal pancreatic tissue.

    研究发现在肿瘤组织中大约有100种不同的miRNA通常表达水平非常高,而它们在正常胰腺组织的中水平并不高。

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  • Computer analysis of the data identified a pattern of miRNAs that were present at increased or decreased levels in pancreatic tumor tissue compared with normal tissue.

    计算机分析这些数据后鉴别出了一种miRNA表达模式,表现为胰腺肿瘤组织与正常组织相比各种不同miRNA表达水平的升高或降低。

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  • Computer analysis of the data identified a pattern of miRNAs that were present at increased or decreased levels in pancreatic tumor tissue compared with normal tissue.

    计算机分析这些数据后鉴别出了一种miRNA表达模式,表现为胰腺肿瘤组织与正常组织相比各种不同miRNA表达水平的升高或降低。

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