• CONCLUSION Punica granatum L. has protective effect against rat liver microsomal lipid peroxidation.

    结论石榴大鼠微粒体脂质过氧化具有保护作用

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  • OBJECTIVE To investigate the protective effect of Punica granatum L. on rat liver microsomal lipid peroxidation.

    目的研究石榴皮提取物大鼠微粒体脂质过氧化损伤保护作用

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  • The effects of sodium dodecyl sulfonate (SDS) on lipid peroxidation in rat liver microsomal system has been studied.

    文章报告阳离子表面活性剂十二烷基硫酸钠(SDS)鼠肝微粒体脂质过氧化模型影响

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  • Oxidative stress after PH can not only impede hepatocellular proliferation, but also damage liver microsomal CYP450.

    PH引起的氧化应激和炎症因子不仅阻碍细胞增殖损伤微粒体CYP450酶。

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  • An example of a flavoprotein undergoing a one-electron transfer is with the microsomal NADPH-cytochrome P450 reductase.

    经历一个单电子转移黄素蛋白的例子微粒NADPH-细胞色素P 450还原酶。

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  • Objective: to study the effects of trans-resveratrol and trans-piceid on liver weight, contents of microsomal protein and cytochrome P450.

    目的研究反式白藜芦醇反式白藜芦醇苷对大鼠质量、肝微粒蛋白质及细胞色素P 450影响

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  • The effect of Oxymatrine(OMT), isolated from Sophora flavescens Ait, on the hepatic microsomal drug-metabolism enzyme have been investigated.

    氧化中药苦中提取的一种生物碱,本文就其对小鼠微粒体药物代谢的影响进行了探讨。

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  • CONCLUSION:DZ inhibited the 4 hydroxytative metabolic pathway of AP, suggesting DZ may be a potent and selective microsomal enzyme inhibitor.

    结论DZ选择性地抑制AP在人体肝脏中的4羟基代谢途径提示DZ作用较的、选择性的肝药抑制剂。

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  • The results indicate that CBD exerts toxic effect on the macrophages of rat and mouse and the toxicity may be altered by liver microsomal MFO.

    这些结果表明CBD鼠类噬细胞具有毒性作用并且可能肝微粒体混合功能氧化酶的影响。

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  • Objective: to investigate the effects of the ethyl acetate extract of Semen Hoveniae capsule on liver microsomal cytochrome P450 system in rats.

    目的观察枳煿子乙酸乙酯提取物胶囊微粒体细胞色素P 450及其同工酶的影响

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  • Alcohol, the most common cause, is a hepatotoxin that interferes with mitochondrial and microsomal function in hepatocytes, leading to an accumulation of lipid.

    乙醇常见病因,作为毒素能阻碍肝细胞内线粒体微粒体的功能,导致脂质沉集。

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  • Hepatic microsomal enzyme and culture solution of intestinal bacteria produced from rat feces were used for the research of metabolism of stilbene glycoside in vitro.

    采用微粒体温孵大肠杆菌培养方法二苯乙烯进行体外代谢研究

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  • METHODS The metabolic transformation of glaucocalyxin A was studied by using rat liver microsomal incubation containing the NADPH-generating system in vitro and in rat bile.

    方法采用大鼠肝微粒体体外温孵法,研究蓝萼甲素的代谢转化

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  • Objective to explore acrylonitrile (ACN) induced DNA damage on Newt spermatogonia, and to compare the difference in DNA damages before and after microsomal enzyme activation.

    目的探讨丙烯腈(acn)睾丸原细胞dna损伤作用经肝微粒体活化前后损伤程度的差异

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  • The results suggested that the inhibition of hepatic microsomal drug-metabolizing enzymes by cadmium, lead or mercury was produced by decreased neosynthesis of microsomal enzymes.

    结果提示可能通过降低微粒新生合成,抑制微粒体药物代谢酶。

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  • Slentrol is a new chemical entity called a selective microsomal triglyceride transfer protein inhibitor, which blocks the assembly and release of lipoproteins into the bloodstream.

    Slentrol一种新型化学物质选择性微粒体甘油三酸酯转移蛋白抑制剂阻断脂蛋白血液中的合成释放

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  • Conclusion Chronic intermittent hypoxia can increase rat liver microsomal ERD and ANH activities. The mechanism is related to up-regulation of CYP3A2 and CYP2E1 expression at the transcriptive levels.

    结论慢性间断性低氧明显增加大鼠肝脏erd (CYP3A2)ANH (CYP2E1)活性机制可能与其转录水平上提高肝脏cyp3a2和CYP2E1基因表达水平有关。

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  • Conclusion Chronic intermittent hypoxia can increase rat liver microsomal ERD and ANH activities. The mechanism is related to up-regulation of CYP3A2 and CYP2E1 expression at the transcriptive levels.

    结论慢性间断性低氧明显增加大鼠肝脏erd (CYP3A2)ANH (CYP2E1)活性机制可能与其转录水平上提高肝脏cyp3a2和CYP2E1基因表达水平有关。

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