The preparation method adopts the silicon and non-silicon compounding method for preparing the hollow metal micro-needle, and the processing cost is low.
本发明采用硅与非硅复合方法制备空心金属微针，加工成本低。
Abstract: Objective to observe the clinical effect of micro-needle therapy in the treatment of refractory melasma.
[摘要]目的：观察微针疗法治疗难治性黄褐斑的临床疗效。
The observation group was treated with micro-needle at scalp hairline region; the control group was administered oral medicine.
观测组用头皮发际区微针法，对照组用口服药物疗法。
Conclusion Micro-needle therapy is effective, and provides a new method for the treatment of refractory melasma.
结论：微针疗法治疗难治性黄褐斑疗效确切，无明显副作用，为治疗难治性黄褐斑提供了一个新手段。
Conclusion Micro-needle therapy is effective, and provides a new method for the treatment of refractory melasma.
结论：微针疗法治疗难治性黄褐斑疗效确切，无明显副作用，为治疗难治性黄褐斑提供了一个新手段。
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