The effect of Taxol at different concentrations on mdr1 gene transfer cells was determined by FCM.
用FCM检测不同浓度紫杉醇素对基因转导细胞的作用。
AIM: the relationship between multiple drug resistance (MDR1) gene and the volume regulation was investigated.
目的:研究多重耐药(MDR1)基因与细胞容积调节的关系。
Our results demonstrated that the expression of MDR1 seems to be correlated with the response to chemotherapy.
对周血标本的初步检测表明:白血病化疗效果与MDR1表达水平的高低有关。
So MDR1 expression in SKOV3/mdr1 cell line was partially inhibited after MDR1-AS treatment in the mRNA and protein level.
所以导入MDR1基因硫代反义寡聚脱氧核苷酸可以部分抑制SKOV3/mdr1细胞中MDR1基因的表达。
Objective: to study the significance of MDR1 expression in leukemia, and to establish a fast and easy method of MDR1 expression detection.
目的:探讨白血病MDR1表达的意义,建立MDR1检测的简便快速方法。
AIM: To investigate the expression of drug resistance genes, MDR1 and MRP, in patients with primary breast cancer after neoadjuvant chemotherapy.
目的:探讨乳腺癌新辅助化疗对耐药基因mdr1和MRP表达的影响。
Conclusions Moderate dose of verapamil can reverse chemoresistance of pancreatic carcinoma cell line to ADM and MMC that might be related to MDR1.
结论MDR1可能参与胰腺癌细胞株化疗耐药;中等剂量的维拉·帕米联合化疗可逆转具有MDR1表型的人胰腺癌细胞株对adm和MMC的耐药现象。
MDR1 gene was transfered to cord blood nucleate cells (CBNC) mediated by adenovirus vector, for enhancing its resistance to chemotherapeutic drugs.
通过腺病毒载体介导使多药耐药基因转染入脐血有核细胞,提高其对化疗药物的耐受性。
Objective: To establish a radiation-resistant human tongue squamous carcinoma cell line and to detect the expression of multidrug-resistant gene( MDR1) and protein (P-gp).
目的:建立人舌鳞状细胞癌耐放疗细胞系并检测多药耐药基因和蛋白的表达。
Methods MDR1 gene expression in case of 30 leukemia and 8 healthy persons' peripheral blood have been detested by fluorescence-quantitative reverse transcription-polymerase chain reaction (RT-PCR).
方法应用荧光定量逆转录-多聚酶链反应(RT -PCR)检测了30例急性白血病患者和8例正常人外周血MDR1基因的表达。
Methods MDR1 gene expression in case of 30 leukemia and 8 healthy persons' peripheral blood have been detested by fluorescence-quantitative reverse transcription-polymerase chain reaction (RT-PCR).
方法应用荧光定量逆转录-多聚酶链反应(RT -PCR)检测了30例急性白血病患者和8例正常人外周血MDR1基因的表达。
应用推荐