CONCLUSION: AGEP enhanced MCP-1 mRNA expression in human PBMC.
结论:AGEP能增加人血单核巨噬细胞MCP - 1基因的表达。
Antisense MCP-1 decreases MCP-1 transcription and translation.
反义mcp - 1可降低系膜细胞MCP - 1的转录和翻译。
Serum levels of MCP-1 may be used to reflect the severity of myocarditis.
小鼠血清mcp - 1水平可部分反映心肌炎的严重程度。
Conclusion: The MCP-1 may play a pivotal pathogenic role in diabetic nephropathy.
结论:MCP鄄1在糖尿病肾病发病机制中发挥重要作用。
Objective To examine the influence of antisense MCP-1 on MCP-1 production and mesangial cell proliferation.
目的研究反义单核细胞趋化蛋白1 (MCP - 1)对系膜细胞MCP - 1分泌及增生的影响。
CONCLUSION the role of cetirizine on the cutaneous allergy may be related to inhibiting the expression of MCP-1.
结论西替利嗪可能通过抑制趋化因子mcp - 1的表达而发挥抗皮肤过敏作用。
Methods: Using LPS-induced microglia activation model and proinflammatory cytokines NO and MCP-1 were measured by ELISA.
方法:采用体外lps诱导小胶质细胞活化模型,用ELISA法测定细胞外液中NO和MCP - 1的含量。
Objective To explore the effect of Valsartan on expression of MCP-1 in the kidney of diabetic rat and the protective mechanism.
目的:研究缬沙坦对糖尿病大鼠肾脏m CP 1表达的影响,探讨缬沙坦对糖尿病大鼠肾脏的保护作用机制。
Conclusion Bezafibrate could attenuate as in rabbits, in which the decrease of MCP-1 protein and gene expression may be involved.
结论使用苯扎贝特明显减轻了动脉粥样硬化程度,其中MCP - 1基因及蛋白表达的下降具有重要的作用。
Results: A gene fragement encoding MCP-1 was cloned into the fusional expression vector PGEX-2T. DNA sequencing indicated that it was correct.
结果:将编码人单核细胞趋化蛋白—1(MCP—1)基因克隆至融合表达载体pGEX—2T中,DNA测序证实正确。
Objective:To investigate the expression of monocyte chemoattractant protein-1(MCP-1) in hepatocellular carcinoma and the clinical significance.
目的:检测MCP-1在肝细胞性肝癌中表达的状况,分析其与肿瘤血管新生的关系。
Objective To construct replication deficient recombinant adenovirus of human monocyte chemoattractant protein-1 (MCP-1) by homologous recombination.
目的制备表达人单核细胞趋化蛋白- 1 (MCP - 1)复制缺陷型重组腺病毒。
Conclusions: Serum MCP-1 level is elevated in acute myocardial infarction, indicating its role as a marker predicting the rupture of unstable plaques.
结论:急性心肌梗死患者血清mcp 1水平明显增高,是显示斑块不稳定性的重要标志之一。
Methods: The expression of MCP-1 in 41 cases of OSCC and 10 specimens of normal oral epithelial tissue was assessed with SABC immunohistochemical method.
方法:应用免疫组织化学SABC法检测41例口腔鳞癌组织中MCP-1的表达,并以10例正常口腔黏膜组织作为对照。
MCP-1 and MCP-2 were analyzed and determined by phenol-sulfuric acid, m-hydroxyldiphenyl, volumetry, HPGPC, agarose gel electrophoresis, IR and UVmethods.
通过苯酚-硫酸法、间羟基联苯法、高效凝胶渗透色谱法、容量分析法、红外及紫外光谱等手段对MCP-1、MCP-2进行分析测定。
Conclusion the up-regulated expression of MCP-1 and RANTES in transplant kidney tissue may play a role in the pathogenesis of chronic allograft nephropathy.
结论肾组织中MCP 1和RANTES的表达升高可能与慢性移植肾肾病的发生有关。
Objective To investigate the expression of monocyte chemoattractant protein 1 (MCP-1) and RANTES and their significance in the pathogenesis of chronic allograft nephropathy.
目的探讨慢性移植肾肾病大鼠模型肾组织中单核细胞趋化因子1(MCP 1)和RANTES的表达及意义。
Conclusion pravastatin could control and delay the morphological changes of diabetic retinopathy, and pravastatin could decreased the expression of MCP-1 in diabetic retina.
结论普伐他汀能够阻止或延缓糖尿病视网膜形态改变;普伐他汀能够减弱糖尿病大鼠视网膜组织中MCP - 1的表达。
These findings provide evidence that CCR2 and MCP-3/MCP-1 are critical for monocyte mobilization and suggest new roles for monocyte chemoattractants in leukocyte homeostasis.
这些研究给CCR2和MCP-3/MCP-1是单核细胞动员的关键因素提供了证据,并且揭示了单核细胞诱生物在白细胞稳定中的崭新作用。
Objective to observe the preventing function of recombinant human MCP-1 (Monocyte Chemoattractant Protein-1) on the plantation of human osteosarcoma cells and to study the dose.
目的观察重组人单核细胞趋化因子- 1 (MCP - 1)对骨肉瘤细胞种植的预防作用,并探索其作用剂量。
Objective To investigate the expression of osteopontin (OPN) and monocyte chemoattractant protein 1(MCP-1)and the effect of simvastatin on them in diet-hypercholesterolemia rats.
目的观察高脂血症肾损害大鼠肾组织中骨调素(OPN)和单核细胞趋化蛋白1 (MCP-1)表达变化及辛伐他汀对其表达的影响。
Objective To investigate the relationship between insulin resistance and monocyte chemoattractant protein-1 (MCP-1) in patients with coronary heart disease and metabolic syndrome (MS).
目的研究冠心病合并代谢综合征患者胰岛素抵抗与单核细胞趋化蛋白- 1 (MCP - 1)表达的关系。
Objective To evaluate the genotypic distribution of MCP-1-2518A/G single nucleotide polymorphism in the south Han population of Jiang su province and the ethnic differences of this polymorphism.
结论:苏南地区汉族健康人群中MCP-1-2518A/G位点基因型分布和等位基因频率与斯洛伐克、突尼斯、爱尔兰和南非人群相比存在明显的种族差异,但与韩国、墨西哥人群相比无种族性差异。
Objective To study the effect of breviscapine on intercellular adhesion molecule-1 (ICAM-1) and monocyte chemotactic protein-1 (MCP-1) expression in tubulointerstitium of experimental diabetic rats.
目的探讨灯盏花素对糖尿病大鼠肾小管-间质细胞间黏附因子- 1 (ICAM - 1)与单核细胞趋化蛋白- 1 (MCP - 1)表达的影响。
Objective To investigate the effects of advanced glycation end products (AGE) on secretion of monocyte chemoattractant protein-1(MCP-1) by human endothelial cells and its signal transduction pathway.
目的研究晚期糖基化终产物(AGE)修饰蛋白对人内皮细胞分泌单核细胞趋化蛋白1(MCP 1)的影响及其作用的信号传导途径。
Objective To investigate the effects of homocysteine (HCY) on the expression of monocyte chemoattractant protein? 1 (MCP? 1) in endothelial cells.
目的探讨同型半胱氨酸(HCY)对内皮细胞中单核细胞趋化蛋白1 (MCP 1)表达的影响。
Objective To investigate the role of monocyte chemoattractant protein 1(MCP 1) in viral myocarditis (VMC) induced by coxsackievirus Group B Type 3 (CVB3).
目的研究单核细胞趋化蛋白- 1(MCP- 1)在B3型柯萨奇病毒(CVB3)诱导病毒性心肌炎(VMC)发病中的作用。
Chlorophyll in the fruit skin and starch in fruit were also inhibited by application of 1 -mcp.
同时发现,1 - MCP处理抑制了果实中淀粉和果皮叶绿素的转化和分解。
OBJECTIVE: To observe MCP 1 expression in the serum of patients with acute spinal cord injury and explore the possible mechanism of secondary spinal cord injury.
目的:观察急性不完全脊髓损伤患者血清中MCP - 1的表达,探讨继发性脊髓损伤的可能机制。
These results, along with the observed prophylactic effects of 1-MCP, suggest that water-soaking in watermelon fruit is an ethylene-induced senescence phenomenon.
这些结果和1-MCP的预防效果说明,西瓜果实的水渍化败坏是一种由乙烯诱导的衰老现象。
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