• CCK activates MAPK in pancreatic acinar cells.

    在胰腺腺泡细胞CCK可激活MAPK。

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  • ObjectiveTo explore the effect of heat shock response(HSR) on the LPS-stimulated MAPK pathways.

    探讨热休克反应(HSR)对内毒素(LPS)所致MAPK信号通路的影响。

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  • MAPK signaling transduction is a key pathway of cellular proliferation and apoptosis regulation.

    MAPK信号转导通路是一条关键的调节细胞增生和凋亡的通路。

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  • The results suggest that hole might be involved in heart development through MAPK signaling pathway.

    研究表明,该基因可能通过参与MAPK信号途径而在心脏发育的过程中起作用。

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  • Conclusion the proliferation of HFL1 induced by FN was through the MAPK signal transduction pathway.

    结论FN诱导HFL1的细胞增殖可以通过MAPK信号转导途径实现。

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  • Monoclonal antibody is produced by immunizing animals with synthetic phospho-MAPK/CDK substrate peptides.

    该单克隆抗体用合成的磷酸化MAPK/CDK底物多肽免疫动物制备。

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  • MAPK cascade pathway can converge extracellular signals and play an important role in signal transduction.

    MAPK级联途径,具有信号汇总功能,在信号转导过程中起着重要作用。

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  • Objective: to study the mechanisms of oridonin-induced U937 cell apoptosis, and to examine the role of ERK MAPK.

    目的:研究冬凌草甲素诱导人组织淋巴瘤u 937细胞凋亡的机制及ERK激酶在凋亡过程中的作用。

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  • CONCLUSION: MAPK signal transduction pathway participates the proliferation inhibition of cantharidin on A549 cell.

    结论:MAPK信号传导途径参与了斑蝥素对人肺癌a5 49细胞的增殖抑制作用。

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  • For MAPK inhibitor assay plated cells were pretreated with inhibitors for at least 30 minutes before drug was added.

    进行MAPK抑制剂分析时,细胞在加药前用抑制剂处理至少30分钟。

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  • These results indicate that MAPK signaling functions, at least in part, as the inducer of ameloblast differentiation.

    这些结果说明MAPK信号至少部分的诱导了成釉细胞的分化。

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  • The extracellular signal-regulated kinase(ERK) is an important member of mitogen-activated protein kinase(MAPK) family.

    细胞外信号调节激酶是丝裂原激活蛋白激酶家族的重要成员。

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  • CONCLUSION: rat U-II was a potent vasoconstrictor of rat main pulmonary arteries and this response was mediated through MAPK.

    结论:大鼠尾加压素II是大鼠肺主动脉有效的血管收缩剂,细胞信号转导通路MAPK的激活参与其收缩效应。

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  • In hyperosmotic stress, the HOG-MAPK pathway regulates the signal transduction and expression of numerous genes for cell survival.

    该途径在高渗应激环境下控制信号转导和基因表达,是细胞生存所必需的。

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  • Objective to investigate the relationship between P38 MAPK activity and apoptosis in drug-resistant cell line of ovarian carcinoma.

    目的研究卵巢癌细胞耐药过程中P 38MAPK活性与凋亡的关系,探讨P 38 MAPK信号转导途径在卵巢癌细胞耐药中的作用。

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  • Phosphorylation of IRS-1 at Ser612 by MAPK downregulates insulin signaling and may be part of a response to high glucose/glucosamine levels (11).

    1的612位丝氨酸被MAPK磷酸化后会下调胰岛素信号,这可能是对高葡萄糖/葡萄糖胺比值的一种反应。

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  • Objective to investigate the effect of mitogen-activated protein kinase (MAPK) on pathogenesis in myocardium hypertrophy of renal hypertension rats.

    目的探讨丝裂素活化蛋白激酶(MAPK)在肾性高血压致心肌肥大中的作用。

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  • Objective To observe the changes in mitogen-activated protein kinase (MAPK)activity and gene expression after coronary artery balloon injury in rabbits.

    目的探讨丝裂素活化蛋白激酶(MAPK)在动脉球囊损伤后内膜增殖过程中表达的变化。

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  • Aim: to explore the expression and abnormal activation of mitogen-activated protein kinase (MAPK) in the development and progression of cerebral gliomas.

    目的:研究人脑胶质瘤组织中丝裂原激活蛋白激酶(MAPK)的表达及活化情况。

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  • To examine the roles of MAPK signals, we compared the effects of anisomycin and sodium salicylate on the expression of tooth-related differentiation markers.

    为了研究MAPK信号的作用,我们比较了茴香霉素和水杨酸钠作用下牙齿相关的分化标志的表达。

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  • Using special inhibitor and stimulator of MAPK can make help to understand the complex route system and develop a new route to treat cerebral ischemic disease.

    应用MAPK特异性抑制剂和激动剂,有助于进一步认识这一复杂的网络信号传导系统,为临床防治缺血缺氧性疾病提供有效手段和理论依据。

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  • Conclusions the cytotoxic effects of parvovirus H-1 might affect the gene expression involved in MAPK signal transduction pathway in gastric carcinoma HGC27 cells.

    结论细小病毒H 1的细胞毒作用可能与其影响胃癌细胞MAPK信号传导途径中相关基因的表达有关。

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  • The mitogen-activated protein kinase (MAPK) cascade plays an important role in signal conversion and amplification of extracellular stimuli in eukaryotic organisms.

    促分裂原活化蛋白激酶(MAPK)级联途径信号通路在真核生物细胞信号的转换和放大过程中起重要作用。

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  • To investigate the change of mitogen activated protein kinase(MAPK) signaling pathway during prostate cancer progression, and therefore to explore its role on cell proliferation.

    目的:研究前列腺癌进展中细胞丝裂原活化蛋白激酶(MAPK)信号通路的变化,探讨阻断此通路对前列腺癌细胞增殖的影响。

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  • The MAPK which activated through phosphorylation involve several cell life activities, just like the control gene transcription, induce cell death, regulate cell circle and so on.

    经磷酸化活化的丝裂原活化蛋白激酶,可参与多种细胞生命活动,如调节基因转录,诱导细胞凋亡、调节细胞周期等。

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  • Objective To study the effects of high glucose on activity of mitogen activated protein kinase (MAPK) in cultured human mesangial cells and to explain the mechanism of diabetic nephropathy.

    目的:研究高糖对人肾小球系膜细胞丝裂原蛋白激酶(MAPK)活性的影响,探讨其在糖尿病肾病发病中的作用。

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  • Objective to investigate effects of PDGF on phenotypic change of glomerular mesangial cells (MC), and study intracellular mechanisms through mitogen-activated - protein kinase (MAPK) pathways.

    目的研究血小板源生长因子(PDGF)对肾小球系膜细胞(MC)表型转化的影响,并探讨丝裂素活化蛋白激酶(MAPK)信号转导途径在其作用中的调控机制。

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  • Objective To discuss the relationship between estradiol and the mitogenic activated protein kinase signal transduction pathway and the expression of the MAPK in the MCF-7 breast cancer cell-line.

    目的探讨雌二醇与有丝分裂素激活蛋白激酶(MAPK)信号通路的关系以及MAPK在乳腺癌细胞系中的表达情况。

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  • Objective To discuss the relationship between estradiol and the mitogenic activated protein kinase signal transduction pathway and the expression of the MAPK in the MCF-7 breast cancer cell-line.

    目的探讨雌二醇与有丝分裂素激活蛋白激酶(MAPK)信号通路的关系以及MAPK在乳腺癌细胞系中的表达情况。

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