Tulathromycin is a novel macrolide antibiotic for animals which has been approved for use in the prevention and treatment of swine respiratory disease in China.
泰拉霉素是动物专用的新型大环内酯类抗生素，国内已批准用于猪呼吸系统疾病的防治。
Therefore, design and synthesis of new macrolide derivatives against resistant bacteria based on new target sites is an important way to overcome bacterial resistance.
因此，基于新靶点设计合成抗耐药菌大环内酯抗生素，是解决细菌耐药性的一条重要途径。
Natamycin is a kind of polyene macrolide antifungal antibiotic not only specifically represses yeast and fungi but also plays as a natural antiseptic in food and forage industry.
纳他霉素是一种多烯大环内酯类抗真菌抗生素，能专一地抑制酵母和霉菌，作为天然的防腐剂用于食品和饲料行业。
Erythromycin is a broad spectrum macrolide antibiotic and clinically used widely.
红霉素是一类广谱大环内酯类抗生素，在临床上具有广泛的应用。
Objective To establish a method for microbial limit test of macrolide antibiotics.
目的建立大环内酯类抗生素微生物限度检查方法。
Aim to evaluate the cellular mechanism of the anti inflammatory action of macrolide.
目的了解大环内酯抗生素抗炎效应的细胞学机制。
Objective: To study the macrolide antibiotic adverse reaction and safety of drug application.
目的：探讨大环内酯类抗生素的不良反应及用药安全性。
Roxithromycin, a new macrolide antibiotic, has an antibacterial spectrum similar to that of erythromycin.
罗红霉素为新型大环内酯类抗生素，其体外抗菌活性类似于母体化合物红霉素。
Fluoroquinolones and macrolide antimicrobial agents have both been associated with prolongation of the QT interval.
氟代喹诺酮和大环内酯抗菌剂都与QT间期的延长有关。
More than 20 kinds of macrolide antibiotics, which have been used since the early 1950s, have been playing an important role in clinic.
从上个世纪五十年代大环内酯抗生素上市以来，已有20余种用于临床，在抗感染领域发挥着十分重要的作用。
The use of macrolide polyene antibiotics or derivatives or analogues thereof as culture supplement for the propagation of virus is described.
本发明描述了大环内酯多烯抗生素或其衍生物或类似物作为培养物补充物用于病毒繁殖的用途。
The present invention is new technological process of preparing erythromycin A-9-oxime compound as one intermediate of macrolide antibiotics.
本发明提供了一种制备大环内酯类抗生素衍生物的一种中间体红霉素A - 9 -肟化合物的制备新工艺。
Erythromycin is the secondary metabolite of Saccharopolyspora erythraea. It is a broad spectrum macrolide antibiotic and clinically used widely.
红霉素是糖多孢红霉菌合成的次生代谢产物，为一类广谱大环内酯类抗生素，在临床上具有广泛的应用。
The adsorption and desorption extraction processes of macrolide antibiotic M- 90 from the fermentation broth by macroreticular adsorbents are discussed.
本文研究用大网格吸附剂从发酵液中提取抗生素M-90的吸附与解吸过程。
Telithromycin, which is the representative of ketolides, has come into market in 2001. It shows very good activity against some macrolide-resistant bacteria.
酮内酯中最具代表性的药物泰利霉素已于2001年成功上市，其对包括大环内酯耐药菌在内的革兰氏阳性菌具有良好的抗菌活性。
The second generation macrolide antibiotics has the satisfactory antibacterial activity and the stability in acid. But the tolerance has been the urgent problem.
第二代大环内酯类抗生素具有良好的抗菌活性和酸稳定性，但是目前耐药性问题成为当务之急。
Persistent fever may be an important correlative factor of extra-pulmonary complications caused by mp, and early therapy of macrolide can reduce the extra-pulmonary complications.
持续发热可能是MP肺外并发症的相关因素之一，早期大环内酯类抗生素的应用可以减少MP肺外并发症的发生。
Studies showed that macrolide antibiotics exert antimicrobial effects by binding to L27 and L22 protein of the 50s subunit of bacterial ribosomes and inhibiting protein synthesis.
研究表明，大环内酯类抗生素能与细菌核糖体50s亚单位的L 2 7及L 2 2蛋白质结合，抑制细菌的蛋白合成而发挥抗菌作用。
Studies showed that macrolide antibiotics exert antimicrobial effects by binding to L27 and L22 protein of the 50s subunit of bacterial ribosomes and inhibiting protein synthesis.
研究表明，大环内酯类抗生素能与细菌核糖体50s亚单位的L 2 7及L 2 2蛋白质结合，抑制细菌的蛋白合成而发挥抗菌作用。
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