The study also provided so insight into the cellular and molecular mechanisms involved when LTB4 stimulates neuronal stem cells.
这项研究对LTB4刺激神经干细胞的细胞和分子机制也有深入研究。
Methods 5- LO products, leukotriene B4 (LTB4) and 5 hydroxyeicosatetraenoic(5-HETE), we re determined by RP-HPLC to represent 5-LO activity.
方法采用反相高效液相色谱法检测5-脂氧合酶产物——白三烯B4和5-羟花生四烯酸量的变化来反映该酶活性的改变。
Objective To determine whether leukotriene B4 (LTB4) could directly stimulate human osteoclast differentiation and activation independent of RANKL (ODF).
目的探讨白三烯（LT）B4能否不依赖细胞核因子资B受体激活剂配体（RANKL）直接促进人破骨细胞的分化和激活。
While inhibiting LTB4 might be a good thing, to simultaneously block LTA4H's ability to degrade PGP defeats the purpose, and may make the situation worse.
虽然抑制LTB4可能是一件好事情，但同时抑制了LTA4H对PGP的降解能力，可能使得这一良好愿望落空，甚至使情况恶化。
"Drugs are in design that would reduce LTB4 by shutting down LTA4H," he said. "But we now know that LTA4H has a beneficial role to play in the reduction of PGP."
他说：，目前正在设计通过关闭LTA4H降低LTB4的药物，但我们现在知道了LTA4H在降低PGP的方面具有积极的作用。
LTB4 is one of the metabolites of arachidonic acid via 5-Hpoxygenase pathway. lt is a potent inflammatory mediator and is related to actions of leukocytes in hypersensitive reactions.
花生四烯酸代谢产物白三烯B_4与炎症及过敏反应中白细胞的各种活动密切相关。筛选有效的白三烯B_4抑制荆可为临床提供抗炎抗过敏反应的一代新药。
LTB4 production by PMNL also showed an increasing tendency in both cerebral thrombosis and acute myocardial infarction, but was not altered in cerebral hemorrhage of non-infarction coronary disease.
急性脑血栓与急性心肌梗塞pmnl的LTB_4生成也有增加的趋势，但脑溢血与非梗塞冠心病无明显改变。
LTB4 production by PMNL also showed an increasing tendency in both cerebral thrombosis and acute myocardial infarction, but was not altered in cerebral hemorrhage of non-infarction coronary disease.
急性脑血栓与急性心肌梗塞pmnl的LTB_4生成也有增加的趋势，但脑溢血与非梗塞冠心病无明显改变。
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