OBJECTIVE To prepare Lomustine thermo-sensitive liposomes (CCNU-TSL) and investigate the anti-tumor activity in vitro.
目的制备洛莫司汀热敏脂质体并考察其体外抗肿瘤活性。
CONCLUSION the drug release percents and the tumor control rates of CCNU-TSL are improved significantly compared with lomustine solution in vitro.
结论洛莫司汀热敏脂质体在相变温度时，体外释药明显增加，体外抑瘤效果明显提高。
CONCLUSION the drug release percents and the tumor control rates of CCNU-TSL are improved significantly compared with lomustine solution in vitro.
结论洛莫司汀热敏脂质体在相变温度时，体外释药明显增加，体外抑瘤效果明显提高。
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