Lomustine liposomes were prepared by the reversed-phase evaporation method.
采用逆相蒸发法制备洛莫司汀脂质体。
OBJECTIVE To prepare Lomustine thermo-sensitive liposomes (CCNU-TSL) and investigate the anti-tumor activity in vitro.
目的制备洛莫司汀热敏脂质体并考察其体外抗肿瘤活性。
CONCLUSION the drug release percents and the tumor control rates of CCNU-TSL are improved significantly compared with lomustine solution in vitro.
结论洛莫司汀热敏脂质体在相变温度时，体外释药明显增加，体外抑瘤效果明显提高。
Chemotherapy was given according to the protocol which consisted of lomustine, cisplatinum and vincristine after radiotherapy, but the patients were not given intrathecal chemotherapy.
所有患儿于放疗后接受长春新碱、环己亚硝脲、顺铂方案化疗，所有患者均未行鞘内化疗。
Chemotherapy was given according to the protocol which consisted of lomustine, cisplatinum and vincristine after radiotherapy, but the patients were not given intrathecal chemotherapy.
所有患儿于放疗后接受长春新碱、环己亚硝脲、顺铂方案化疗，所有患者均未行鞘内化疗。
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