Method Plasma concentrations of 9-nc lactone form (lactone 9-nc) and the total of lactone and carboxylate forms (total 9-nc) were determined by the validated HPLC method.
方法：采用hplc法测定大鼠尾静脉注射给药后不同时间点9 - NC的内酯型浓度和总浓度并进行药物动力学拟合。
Method Plasma concentrations of 9-nc lactone form (lactone 9-nc) and the total of lactone and carboxylate forms (total 9-nc) were determined by the validated HPLC method.
方法：采用hplc法测定大鼠尾静脉注射给药后不同时间点9 - NC的内酯型浓度和总浓度并进行药物动力学拟合。
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