Both frameshift and missense mutations can be suppressed by intragenic suppressors.
移码突变和异义突变都能被基因内抑制基因所抑制。
Both frameshift and missense mutations can be suppressed by intragenic suppressors.
两个突变发生在同一基因内的抑制，叫基因内抑制。
It is necessary to detect the large intragenic MMR genes deletions in the molecular detection of HNPCC.
在分子遗传学检测中有必要开展MMR基因大片段缺失的检测。
The intragenic and extragenic recombination results in variation. Recombination also is involved in generation novel resistance specificities.
基因间和基因内重组导致了变异，也导致了新特异性抗病基因的产生。
Methods: Using the polymerase chain reaction technique (PCRT), LOHs in 10 samples of hereditary ovarian cancer at intragenic loci were detected.
方法：应用多聚合酶链反应技术(PCRT)，对10份遗传性卵巢癌组织中BRCA1基因内部的D17S855微卫星位点进行LOH检测。
Conclusions No functional FANCA protein was found in these 3 cases of FA-A, and intragenic deletion, frame shift and splice site mutation were the major pathogenic mutations found in FANCA gene.
结论3例FA-A型患者均无功能性FANCA蛋白表达；基因缺失、移码突变和剪切位点突变是FANCA基因的主要失活方式。
Conclusions No functional FANCA protein was found in these 3 cases of FA-A, and intragenic deletion, frame shift and splice site mutation were the major pathogenic mutations found in FANCA gene.
结论3例FA-A型患者均无功能性FANCA蛋白表达；基因缺失、移码突变和剪切位点突变是FANCA基因的主要失活方式。
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