Conclusions BMP might not only induce differentiation of mesenchymal cells, but also stimulate the formation of blood vessels.
结论BMP不仅可诱导间质细胞向成骨细胞分化,而且也可以刺激血管的形成。
Targeting peroxiredoxin I/II by Adenanthin, a naturally occurring diterpenoid, to induce differentiation and eradicate leukemia-initiating cells of acute promyelocytic leukemia.
靶向过氧化物酶I/II,一种天然二帖类物质,诱导分化和根除急性早幼粒细胞白血病。
Methods Induce the differentiation of erythroleukemia cell line HB60-5 to mature erythroid cells by altering the culture condition and plot a cell growth curve.
方法利用红白血病细胞株hb60 - 5的生长特性,通过改变培养条件,促使细胞向成熟细胞分化。
It was found that these three compounds can induce the differentiation of HL-60 cells in vitro, judged by cell growth inhibition, morphologic observation and NBT reduction ability.
结果表明,在适当的用药浓度下,从细胞生长抑制情况、形态学观察及NBT还原能力测定判断,三种药物对HL - 60细胞有明显的诱导分化作用。
Embryonic chick skeletal muscle extract was used to induce the differentiation of the neural stem cells into cholinergic neurons.
用鸡胚骨骼肌提取液,诱导神经干细胞向胆碱能神经元方向分化。
CONCLUSION: ATRA cannot induce HL 60 to achieve terminal differentiation, but the differentiation of HL 60 can be induced by ATRA and the differentiated leukemia cells are easy to apoptosis.
结论:ATRA并不能诱导HL-60细胞完成终端分化,但是该药可以诱导白血病细胞向成熟方向分化,而且已分化的肿瘤细胞于发生凋亡。
BMP may induce mesenchymal cells to differentiate into chondrocytes, promote the synthesis of extracellular matrix and inhibit the terminal differentiation of chondrocytes.
BMP分子可以诱导间充质细胞分化为软骨细胞,促进合成细胞外基质,抑制软骨细胞的终末分化。
In vitro AOPP may directly induce the osteoblast differentiation of HASMC.
这可能与AOPP直接诱导动脉平滑肌细胞向成骨细胞分化有关。
Agents that induce cell differentiation have been widely used in tumor research and achieved progress in the prevention and treatment of tumor. among them, retinoid drug shows confirmative effect.
分化诱导剂被广泛应用于肿瘤的研究,在肿瘤的预防和治疗方面取得一定的进展,其中以维甲酸类药物效果肯定。
ATRA could induce morphological differentiation and inhibit growth of SY5Y cells and showed time and dose dependent manner.
ATRA对SY5Y细胞有抗增殖作用和诱导细胞分化作用,并呈一定时间和剂量依赖关系。
"This study also suggests a possible way to induce mesenchymal stem cell differentiation into bone cells, which may have long-term implications for regenerative medicine for bone disease, " Hung said.
本研究也提示了诱导间叶干细胞分化成为骨细胞的一种可能方式,这对于治疗骨病的再生医学而言可能具有长远的影响意义。
An ideal pulp capping agent should have properties to induce odontoblast differentiation and reparative dentinogenesis.
理想的盖髓材料应具有诱导牙髓细胞分化、修复性牙本质形成和保存活髓的特性。
Conclusion a reconstructed dermal substrate could induce epidermal regeneration, development and differentiation in vitro.
结论用去表皮的真皮组织可以诱导表皮的再生、发育和分化。
It is new for traditional Chinese medicine to induce stem cell differentiation into cardiomyocytes. With deep research, more and more traditional Chinese medicine inducer will be found.
中药在诱导干细胞分化为心肌细胞方面的研究较新,随着研究深入,将会有越来越多的中药诱导剂被发现。
Purpose: Histone deacetylase inhibitors (HDACi) are being studied in clinical trials with the aim to induce cellular differentiation, growth arrest, and apoptosis of tumor cells.
目的:临床试验中对组蛋白脱乙酰基酶阻滞剂(HDACi)的研究目的在于诱导细胞分化,生长停止,和肿瘤细胞的凋亡。
CONCLUSION DADS can induce human leukemia HL 60 cells differentiation, and suppression subtractive hybridization (SSH) technique is an effective method to isolate those differentially expressed genes.
结论DADS能诱导人白血病HL 6 0细胞分化,并引起相关的基因发生改变,而抑制性消减杂交技术能有效地分离差异表达的基因。
It was supposed that the aging primary laticifers would produce signals to induce the differentiation of the secondary laticifers.
笔者假定,这种正在变老的初生乳管会产生导致次生乳管分化的信息。
Excessive zinc could significantly induce cytotoxicity and inhibit cell differentiation.
缺锌及过量锌均可抑制细胞的分化并产生毒性作用。
Conclusions SPB can apparently inhibit the proliferation of C6 cells and can induce cell differentiation and even apoptosis of C6 cells.
结论苯丁酸钠可明显抑制C6细胞增殖,诱导细胞分化,甚至诱发细胞凋亡。
The effect on survival and differentiation of human fibroblast GM5758 induce by one and two fractional X-ray irradiation was studied.
研究了单次和两次X射线辐照对人皮肤成纤维细胞GM5 75 8的存活和分化影响。
Conclusion: Tunicamycin could induce RPMI-8226 cell differentiation for mature stage.
结论:衣霉素可使RPMI- 8226细胞向成熟阶段分化。
Results: ICA could inhibit the telomerase activity and induce the differentiation and restrain the proliferation of HL-60 cells. The effect was promoted by ATRA.
结果:ICA可明显抑制端粒酶活性,对白血病细胞均有较明显的诱导分化和抑制增殖作用,且与A TRA合用可产生明显的协同效应。
HDAC and histone deacetylase inhibitors (HDI) can affect expression of some specific genes and induce cell differentiation growth arrest and apoptosis through regulating histone acetylation level.
组蛋白脱乙酰基酶与组蛋白脱乙酰基酶抑制剂通过对组蛋白乙酰化水平的调控,影响特定基因的表达,改变细胞周期的进程。
HDAC and histone deacetylase inhibitors (HDI) can affect expression of some specific genes and induce cell differentiation growth arrest and apoptosis through regulating histone acetylation level.
组蛋白脱乙酰基酶与组蛋白脱乙酰基酶抑制剂通过对组蛋白乙酰化水平的调控,影响特定基因的表达,改变细胞周期的进程。
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