In total despair, the prisoner believed that no one in the world would trust him any more.
囚犯万念俱灰，心想，这世界上再也不会有人相信他了。
In total despair, the prisoner believed that no one in the world would trust him any more. So he escaped from prison that night.
在绝望中，犯人相信这个世界不会再有人相信他。所以那天晚上他越狱了。
If you don't let me heal this time, I humbly pray: Please have me killed! I am in total despair, please acquit me of the torment, God …
假如此次再不让自己康复那么求求你请杀啦自己吧失望啦放过自己…
I'm currently going through a relationship breakup and when I first started to go through it I found myself in total despair on an emotional level.
目前，我正面临着一段关系的破裂。当我第一次经历分手的时候，我发现我自己对感情彻底绝望了。
More than any other time in history, mankind faces a crossroads. One path leads to despair and utter hopelessness. The other, to total extinction. Let us pray we have the wisdom to choose correctly.
比起历史上的任何一个时刻，此时人类面临抉择的十字路口，一条通往绝望的深渊，而另一条则通往毁灭，让我们一起祈祷，希望我们有作出正确决定的智慧。
More than any other time in history, mankind faces a crossroads. One path leads to despair and utter hopelessness. The other, to total extinction. Let us pray we have the wisdom to choose correctly.
比起历史上的任何一个时刻，此时人类面临抉择的十字路口，一条通往绝望的深渊，而另一条则通往毁灭，让我们一起祈祷，希望我们有作出正确决定的智慧。
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