Methods In situ single pass perfusion model was used and the concentrations of three components in perfusate were determined by HPLC in combination with diode array detection.
方法运用单向灌流模型并采用HPLC法（配备二极管阵列检测器）同时测定莪术油中三成分在灌流液中的浓度。
CONCLUSION In situ liver perfusion is an appropriate organ model for drug metabolism and disposition research.
结论大鼠原位肝灌流是良好的整体器官药物代谢模型，是体外实验有力的补充。
METHODS the model of in situ intestinal perfusion was used. A HPLC method was established to determine the drug concentration in the perfusate.
方法采用大鼠在体肠吸收模型，以高效液相色谱法测定循环液中药物的浓度。
METHODS the model of in situ intestinal perfusion was used. A HPLC method was established to determine the drug concentration in the perfusate.
方法采用大鼠在体肠吸收模型，以高效液相色谱法测定循环液中药物的浓度。
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