Objetive to construct human IL 12 efficient expression vector.
目的构建人il -12的高效表达载体。
Objectives To establish the mouse heart transplantation model and observe the effect of anti rejection of IL 12 antibody.
目的建立小鼠心脏移植模型,观察白细胞介素12 (IL 12)抗体的抗排斥作用。
Conclusion Local administration of IL 12 into the portal system would be a useful strategy for the liver metastasis treatment.
结论通过门静脉系统局部应用IL 12是治疗肝转移肿瘤的有效方法。
Objective To investigate the effect of IL 12 antisense oligonucleotides on immunoglobulin secretion by PBMC from patients with active lupus nephritis (LN).
目的探讨IL 12反义寡核苷酸对狼疮肾炎(LN)患者单个核细胞(PBMC)分泌免疫球蛋白的影响。
Conclusion: This method can be applied to measuring the bioactivity of the il 12 and thereby assessing the expression capability of the constructed vectors.
结论:可直接测得il 12的生物活性,并能由此对所构建的载体的表达能力进行分析。
Objective to construct a polycistronic retroviral vector containing both subunits cDNA of murine IL 12 and NeoR gene and investigate their expressions in murine hepatoma cells.
目的构建含小鼠白细胞介素12双亚基及新霉素磷酸转移酶基因多顺反子逆转录病毒载体,并观察其在小鼠肝癌细胞中的表达。
Conclusion Both IL 2 and IL 12 are able to inhibit the growth of mice H22 hepatocellular carcinoma grafted subcutaneously and induce the host anti tumor immune response efficiently.
结论IL 12、IL2基因治疗可抑制小鼠肝癌H 2 2皮下移植瘤的生长,提高机体的抗肿瘤免疫应答,两者联合运用可产生协同效应。
Interleukin-12 (IL-12) is a recently characterized heterodimeric cytokine composed of two subunits.
白细胞介素-12是一种异二聚体细胞因子。
The main Indian contingent will comprise 33 officers and 65 personnel below officer rank, while the support team of IL-76 and IL-78 MKI include an additional 12 officers and 26 others.
印度主要的特遣队将包括33名军官和65名军官以下级别的人员,同时IL-76和IL-78MKI的支持团队将包括额外的12名军官和26名其他人员。
The therapeutic effect of sinomenine on rheumatoid arthritis may be related to its inhibition to secretion of IL-12 in DCs.
青藤碱的抗类风湿作用可能与其抑制树突状细胞分泌白细胞介素12有关。
Levels of serum IL-12 in early stage helps us in prognosticating the disease and guiding in clinical diagnosis and treatment.
早期检测血清il - 12水平,可判断病情的预后,并指导临床的诊断及治疗。
Methods: the rats were immunized by the major surface glycoprotein (MSG) of Pneumocystis carinii combined with IL - 12 as an adjuvant.
方法:用IL-12作为佐剂和卡氏肺孢子虫主要表面糖蛋白(MSG)一起免疫大鼠。
Objective: To study the clinical significance of serum interleukin-12 (IL-12) in patients with viral hepatitis.
目的:探讨病毒性肝炎患者血清中il - 12的改变及其临床意义。
Objective To study the method of immunotherapy against t cell lymphoma by tumor cells transfected by GM-CSF gene combined with interleukin 12 (IL-12).
目的探讨用转粒细胞巨噬细胞集落刺激因子(GM CSF)基因瘤苗,联合白介素12 (IL 12)治疗小鼠t细胞淋巴瘤的方法。
Objective: to detect expression of interleukin - 23 (il - 23) and il - 12 subunits in various leukemia cell lines and evaluate the ability of phorbol diester to up - regulate the subunits expression.
目的:检测人白细胞介素-23 (IL - 23)和白细胞介素-12 (IL - 12)亚基在各类白血病细胞系中的表达并探讨佛波二酯对IL - 23和IL - 12亚基表达的调控作用。
Objective To investigate the antitumor activity of cord blood mononuclear cells(CBMC) activated by interleukin-2 (IL-2)in combination with interleukin-12 (IL-12).
目的探讨白细胞介素-2(IL-2)联合白细胞介素-12(IL-12)对人脐血单个核细胞(CBMC)抗肿瘤作用的影响。
"These results suggest that therapeutics that target the IL-12 and IL-23 signaling pathway appear to effectively treat both psoriasis and IBD," he said.
“这些结果提示了针对白介素- 12和白介素- 23信号通路的治疗方法可能对银屑病和IBD均有效。”他说。
Objective To observe the influence of ultraviolet C(UVC) irradiation on apoptosis of human peripheral blood monocytes and interleukin-2(IL-2), interleukin-12(IL-12).
目的观察短波紫外线(UVC)照射正常人外周血单个核细胞凋亡及白细胞介素2(IL- 2) 、IL- 12 水平的影响。
Objective To investigate the treatment of spontaneous metastatic lung cancer by tumor antigen-pulsed, interleukin-12(IL-12) gene-modified dendritic cells (DC).
目的探讨肿瘤多肽致敏的白介素12 (IL 12 )基因修饰的树突状细胞(DC)对自发性肺转移癌的治疗作用。
Thus, IL-12 is a crucial bridge between innate and adaptive immunity.
因此,IL ? 12被成为天然免疫和获得性免疫之间的桥梁。
Objective: To study the change of plasma level of IL-12 in patients with severe thermal injury.
目的:研究严重烧伤后血浆IL-12浓度的变化及其意义。
Objective To examine the in vitro antitumor activity of normal human peripheral blood mono-nuclear cells(PBMC) induced by interleukin-2(IL-2) and IL-12.
目的检测白细胞介素-2(IL-2)联合IL-12诱导人外周血单个核细胞(PBMC)体外抗肿瘤作用。
Results: IL-12 and IL-18 induced prominent spleen deficiency syndrome similar with that induced by reserpine.
结果:IL - 12及IL - 18引起明显脾虚证的表现,与利血平制作脾虚动物模型组相似。
Objective To detect the level of interleukin(IL-10)and IL-12 in the serum of patients with atopic dermatitis and investigate the role of them.
目的研究血清中白介素-10(IL-10)及白介素-12(IL-12)水平与异位性皮炎的关系。
Objective to detect the level of interleukin (IL) -12 and IL-10 in the serum patients with progressive psoriasis vulgaris and to investigate the role them.
目的研究血清中白介素- 12 (IL - 12)及白介素- 10 (IL - 10)水平与寻常性银屑病的关系。
Conclusion Ganoderan can inhibit the excretion of IL-12 in adjuvant arthritis rats serum.
结论灵芝多糖可明显抑制佐剂性关节炎大鼠血清il - 12的分泌。
In summary, IL-12 cytokine family plays distinct roles in anti-tumor immune responses and has become a focus of study in the research and immune therapy of tumors.
总之,IL - 12细胞因子家族成员在肿瘤免疫反应中各自发挥不同的作用,已成为肿瘤免疫治疗和研究的热点分子。
To explore the changes of NK, IL-12 and CRP levels in pregnancy with preeclampsia and its clinical significance.
目的测定子痫前期孕妇外周血nk、IL - 12、CRP水平的变化并探讨其意义。
Abstract: Objective to investigate the effect of IL-12 on mediator release from mast cells and the potential signal transduction pathways correspondingly.
目的:检测IL - 12对肥大细胞介质分泌的影响并探讨其可能的信号转导通路。
Abstract: Objective to investigate the effect of IL-12 on mediator release from mast cells and the potential signal transduction pathways correspondingly.
目的:检测IL - 12对肥大细胞介质分泌的影响并探讨其可能的信号转导通路。
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