Duerr and colleagues (2006) have reported that the same variant in the IL-23 receptor is associated with IBD.
Duerr及其同事(2006)已报道了IBD相关遗传多态性,同样白介素- 23受体的突变。
ConclusionThe level of serum IL-23 is significantly elevated in patients with SLE, and proper treatments can make it decrease.
结论IL - 23在SLE患者血清中表达水平明显增高,治疗后下降,提示IL - 23可能参与sle的发病。
"These results suggest that therapeutics that target the IL-12 and IL-23 signaling pathway appear to effectively treat both psoriasis and IBD," he said.
“这些结果提示了针对白介素- 12和白介素- 23信号通路的治疗方法可能对银屑病和IBD均有效。”他说。
The identification of this protein, called interleukin-23 (IL-23), is an important finding that gives researchers a specific target for developing new therapies.
这种命名为IL-23的蛋白质是一个重要的发现,因为它给研究者研制新的治疗药物带来一个特异性的方向。
The identification of specific inflammatory mediators like IL-23 opens the door to developing targeted anti-inflammatory treatments which may have fewer side effects.
鉴定象IL-23一样的特异性炎症介质打开了新的靶向抗炎治疗的大门,并大大减少副作用。
Objective: to measure the expression of IL-23 and IL-12 in mice with disseminated candidiasis, in order to understand the role of IL-23 in the anti-systemic Candida albicans infection.
目的了解系统性白念珠菌感染小鼠il - 12和IL - 23的表达特征,探讨IL - 23在抗白念珠菌系统感染中的作用,并重新认识和评价IL - 12的作用。
Objective: to detect expression of interleukin - 23 (il - 23) and il - 12 subunits in various leukemia cell lines and evaluate the ability of phorbol diester to up - regulate the subunits expression.
目的:检测人白细胞介素- 23 (IL - 23)和白细胞介素-12 (IL - 12)亚基在各类白血病细胞系中的表达并探讨佛波二酯对IL - 23和IL - 12亚基表达的调控作用。
Objective to investigate the therapeutic effects on pancreatic carcinoma by dendritic cells (DCs) transfected with interleukin (IL) -23 and acquiring apoptotic cell antigen.
目的探讨白细胞介素23 (IL - 23)基因转染的树突状细胞(DC)负载凋亡癌细胞抗原后诱导的免疫应答对小鼠胰腺癌的治疗作用。
Objective to investigate the therapeutic effects on pancreatic carcinoma by dendritic cells (DCs) transfected with interleukin (IL) -23 and acquiring apoptotic cell antigen.
目的探讨白细胞介素23 (IL - 23)基因转染的树突状细胞(DC)负载凋亡癌细胞抗原后诱导的免疫应答对小鼠胰腺癌的治疗作用。
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