• Interleukin-12 (IL-12) is a recently characterized heterodimeric cytokine composed of two subunits.

    白细胞介素-12是一种异二聚体细胞因子。

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  • Thus, IL-12 is a crucial bridge between innate and adaptive immunity.

    因此,IL ? 12被成为天然免疫和获得性免疫之间的桥梁。

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  • Conclusion Ganoderan can inhibit the excretion of IL-12 in adjuvant arthritis rats serum.

    结论灵芝多糖可明显抑制佐剂性关节炎大鼠血清il - 12的分泌。

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  • Objective: To study the change of plasma level of IL-12 in patients with severe thermal injury.

    目的:研究严重烧伤后血浆IL-12浓度的变化及其意义。

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  • Conclusion The two subunits of IL-12 are successfully linked with linkage peptide by using this method.

    结论:利用该基因分子拼接技术成功地将人白介素12两个亚基基因通过连接肽基因进行拼接。

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  • Results: IL-12 and IL-18 induced prominent spleen deficiency syndrome similar with that induced by reserpine.

    结果:IL - 12及IL - 18引起明显脾虚证的表现,与利血平制作脾虚动物模型组相似。

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  • Objective: To study the clinical significance of serum interleukin-12 (IL-12) in patients with viral hepatitis.

    目的:探讨病毒性肝炎患者血清中il - 12的改变及其临床意义。

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  • To explore the changes of NK, IL-12 and CRP levels in pregnancy with preeclampsia and its clinical significance.

    目的测定子痫前期孕妇外周血nk、IL - 12、CRP水平的变化并探讨其意义。

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  • The therapeutic effect of sinomenine on rheumatoid arthritis may be related to its inhibition to secretion of IL-12 in DCs.

    青藤碱的抗类风湿作用可能与其抑制树突状细胞分泌白细胞介素12有关。

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  • Levels of serum IL-12 in early stage helps us in prognosticating the disease and guiding in clinical diagnosis and treatment.

    早期检测血清il - 12水平,可判断病情的预后,并指导临床的诊断及治疗。

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  • Objective To detect the level of interleukin(IL-10)and IL-12 in the serum of patients with atopic dermatitis and investigate the role of them.

    目的研究血清中白介素-10(IL-10)及白介素-12(IL-12)水平与异位性皮炎的关系。

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  • Objective To study the method of immunotherapy against t cell lymphoma by tumor cells transfected by GM-CSF gene combined with interleukin 12 (IL-12).

    目的探讨用转粒细胞巨噬细胞集落刺激因子(GM CSF)基因瘤苗,联合白介素12 (IL 12)治疗小鼠t细胞淋巴瘤的方法。

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  • "These results suggest that therapeutics that target the IL-12 and IL-23 signaling pathway appear to effectively treat both psoriasis and IBD," he said.

    “这些结果提示了针对白介素- 12和白介素- 23信号通路的治疗方法可能对银屑病和IBD均有效。”他说。

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  • Objective To examine the in vitro antitumor activity of normal human peripheral blood mono-nuclear cells(PBMC) induced by interleukin-2(IL-2) and IL-12.

    目的检测白细胞介素-2(IL-2)联合IL-12诱导人外周血单个核细胞(PBMC)体外抗肿瘤作用。

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  • Abstract: Objective to investigate the effect of IL-12 on mediator release from mast cells and the potential signal transduction pathways correspondingly.

    目的:检测IL - 12对肥大细胞介质分泌的影响并探讨其可能的信号转导通路。

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  • Objective To investigate the treatment of spontaneous metastatic lung cancer by tumor antigen-pulsed, interleukin-12(IL-12) gene-modified dendritic cells (DC).

    目的探讨肿瘤多肽致敏的白介素12 (IL 12 )基因修饰的树突状细胞(DC)对自发性肺转移癌的治疗作用。

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  • Objective To investigate the antitumor activity of cord blood mononuclear cells(CBMC) activated by interleukin-2 (IL-2)in combination with interleukin-12 (IL-12).

    目的探讨白细胞介素-2(IL-2)联合白细胞介素-12(IL-12)对人脐血单个核细胞(CBMC)抗肿瘤作用的影响。

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  • In summary, IL-12 cytokine family plays distinct roles in anti-tumor immune responses and has become a focus of study in the research and immune therapy of tumors.

    总之,IL - 12细胞因子家族成员在肿瘤免疫反应中各自发挥不同的作用,已成为肿瘤免疫治疗和研究的热点分子。

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  • Objective To observe the influence of ultraviolet C(UVC) irradiation on apoptosis of human peripheral blood monocytes and interleukin-2(IL-2), interleukin-12(IL-12).

    目的观察短波紫外线(UVC)照射正常人外周血单个核细胞凋亡及白细胞介素2(IL- 2) 、IL- 12 水平的影响。

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  • A study is intensively made about the influence of the culture conditions for a lactic acid bacterium on the activity of promoting the production of IL-12 from a murine splenic cell.

    本发明针对乳酸菌的培养条件对来自小鼠脾细胞的IL-12的产生促进效果的影响进行了锐意研究。

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  • Objective: to measure the expression of IL-23 and IL-12 in mice with disseminated candidiasis, in order to understand the role of IL-23 in the anti-systemic Candida albicans infection.

    目的了解系统性白念珠菌感染小鼠il - 12和IL - 23的表达特征,探讨IL - 23在抗白念珠菌系统感染中的作用,并重新认识和评价IL - 12的作用。

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  • Objective: to observe the expression of GATA-3in asthmatic mice lungs and to explore the feasibility of interleukin (IL-12) blockading GATA-3expression in treatment of bronchial asthma.

    目的观察t细胞特异转录因子gata - 3在支气管哮喘(哮喘)小鼠肺部的表达,探讨应用白细胞介素12 (IL - 12)阻断GATA - 3表达治疗支气管哮喘的可能性。

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  • Interleukin-12 (IL-12) previously called cytotoxic lymphocyte maturation factor (CLMF) or NK cell stimulatory factor (NKSF) is a recently characterized heterodimeric cytokine composed of two subunits.

    白细胞介素-12(IL-12)最初称作自然杀伤细胞刺激因子(NKSF)或细胞毒性淋巴细胞成熟因子(CLMF),是一种异二聚体细胞因子。

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  • The main Indian contingent will comprise 33 officers and 65 personnel below officer rank, while the support team of IL-76 and IL-78 MKI include an additional 12 officers and 26 others.

    印度主要的特遣队将包括33名军官和65名军官以下级别的人员,同时IL-76和IL-78MKI的支持团队将包括额外的12名军官和26名其他人员。

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  • Objective To investigate the effect of IL 12 antisense oligonucleotides on immunoglobulin secretion by PBMC from patients with active lupus nephritis (LN).

    目的探讨IL 12反义寡核苷酸对狼疮肾炎(LN)患者单个核细胞(PBMC)分泌免疫球蛋白的影响。

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  • Objetive to construct human IL 12 efficient expression vector.

    目的构建人il - 12的高效表达载体。

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  • Objectives To establish the mouse heart transplantation model and observe the effect of anti rejection of IL 12 antibody.

    目的建立小鼠心脏移植模型,观察白细胞介素12 (IL 12)抗体的抗排斥作用。

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  • Methods: the rats were immunized by the major surface glycoprotein (MSG) of Pneumocystis carinii combined with IL - 12 as an adjuvant.

    方法:用IL - 12作为佐剂和卡氏肺孢子虫主要表面糖蛋白(MSG)一起免疫大鼠。

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  • Conclusion Local administration of IL 12 into the portal system would be a useful strategy for the liver metastasis treatment.

    结论通过门静脉系统局部应用IL 12是治疗肝转移肿瘤的有效方法。

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  • Conclusion Local administration of IL 12 into the portal system would be a useful strategy for the liver metastasis treatment.

    结论通过门静脉系统局部应用IL 12是治疗肝转移肿瘤的有效方法。

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