The effect of IGFBP-3 on the growth hormone promoter activity stimulated by triiodothyronine was determined by dual-luciferase reporter assay.
通过双荧光素酶报告基因测定法测定了IGFBP-3对由三碘甲状腺素刺激的生长激素启动子活性的影响。
Inhibiting IGFBP-3 allowed the peptide to exert a more potent effect.
抑制性的IGFBP - 3让肽起一个更有力的作用。
In this study, we have explored the developmental role of IGFBP-3 using the zebrafish model.
本研究使用斑马鱼模型探索了IGFBP - 3的在胚胎发育中的功能。
Methods The serum IGF-1 level was measured by specific radioimmunoassays(RIA); the serum IGFBP-3 level by immunoradio-assays(IRMA).
方法采用放射免疫分析法（RIA）测定血清中IGF-1水平，免疫放射分析法（IRMA）测定IGFBP-3水平。
Conclusions There are positive correlations between serum (IGFBP-3) and age, pubertal stage, height and serum IGF-1 level respectively.
结论血清igfbp - 3水平与年龄、青春发育期、身高及血清igf - 1水平明显相关。
This indicated that the lower IGF-1 and IGFBP-3 levels had no relation with fetal growth, may have relation with the growth retardation after birth.
提示IGF-1／IGFBP-3水平降低与胎儿期体格生长无关； 中义摘要可能与患儿生后生长发育迟缓有关；
Objective to evaluate the relationship between circulating levels of insulin-like growth factor-1 (IGF-1), IGF-binding protein-3 (IGFBP-3) and colorectal cancer.
目的综合评价血清胰岛素样生长因子1 (IGF - 1)、胰岛素样生长因子结合蛋白3 (IGFBP - 3)水平和大肠癌的关系。
In earlier studies, the team found that insulin-like growth factor binding protein-3 (IGFBP-3) binds Humanin and tempers its effects on promotion of cell survival.
在早期研究中，团队发现胰岛素样生长因子结合蛋白- 3 (IGFBP - 3)与人体肽相关，并缓和在促进细胞存活的作用。
Objective to study the relationship between fetal development and cord serum insulin-like growth factor-I (IGF-I), IGF binding protein-3 (IGFBP-3) levels at birth.
目的：探讨新生儿脐血中胰岛素样生长因子- I (IGF - I)和胰岛素样生长因子结合蛋白- 3 (IGF BP - 3)水平与胎儿宫内生长发育的关系。
ObjectiveTo explore the detection significance of insulin-like growth factor-I(IGF-I), IGF-binding protein-3(IGFBP-3) in children with acute lymphoblastic leukemia(ALL).
目的探讨胰岛素样生长因子-Ⅰ（IGF-Ⅰ）及胰岛素样生长因子结合蛋白-3（IGFBP-3）在急性淋巴细胞白血病（ALL）儿童中检测的意义。
Objective: to investigate plasma levels of insulin like growth factor 1 (IGF 1) and its binding protein 3 (IGFBP 3) in type 2 diabetes and their relationship with microangiopathy.
目的：观察2型糖尿病病人血中胰岛素样生长因子-1 (IGF - 1)及胰岛素样生长因子结合蛋白- 3 (IGFBP - 3)水平与糖尿病及微血管病变的关系。
After that, the serum insulin like growth factor 1 (IGF 1), insulin like growth factor binding protein 3 (IGFBP 3), and growth speed were observed.
观察用药后生长速率、血清胰岛素样生长因子-1 (IGF - 1)、血清胰岛素样生长因子结合蛋白3 (IGFBP - 3)等指标的变化。
To observe the clinical value of insulin-like growth factor (IGF) -1 and IGF binding protein (IGFBP) -3 in diagnosis and therapeutic effect judging of growth hormone deficiency (GHD) in children.
目的探讨胰岛素样生长因子1 (IGF - 1)及其结合蛋白3 (IGFBP - 3)在儿童生长激素缺乏症(GHD)诊断及疗效判断中的价值。
Murine serum insulin? Like growth factor1 (IGF? 1) and insulin? Like growth factor binding protein3 (IGFBP? 3) were determined by ELISA.
ELISA方法检测裸鼠血清中胰岛素样生长因子(IGF ？1)和胰岛素样生长因子结合蛋3 (IGFBP ？ 3)含量变化。
Murine serum insulin? Like growth factor1 (IGF? 1) and insulin? Like growth factor binding protein3 (IGFBP? 3) were determined by ELISA.
ELISA方法检测裸鼠血清中胰岛素样生长因子(IGF ？1)和胰岛素样生长因子结合蛋3 (IGFBP ？ 3)含量变化。
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