Conclusions: IGF-2 may contribute to the DM outbreak and the occurrence of osteoporosis.
结论:IGF - 2可能参与了2型糖尿病的进程和骨质疏松的发生。
Methods: Height, weight, fasting serum C-peptide, IGF-2, and BMD were measure in 96 patients with DM.
方法:96例2型糖尿病患者,均测量身高、体质量、骨密度、骨密度以及空腹血清C肽和IGF - 2水平。
There are evidences that IGF-2 increases cell proliferation, inhibits apoptosis and raises local infiltration and transfer in many tumor cells.
有证据证明IGF - 2在许多肿瘤细胞中可使细胞增殖增加,抑制凋亡,增加局部浸润和转移。
IRS-2 is essential for normal nutrient homeostasis because it mediates both peripheral insulin action and the effect of IGF-1 on B-cell growth.
IRS - 2对正常营养动态平衡至关重要,因为它能同时介导外周胰岛素的作用和B -细胞中igf - 1的作用。
In vertebrates, IRS-2 functions as a scaffolding protein to coordinate separate branches of the Insulin/IGF-signaling cascades (2).
在脊椎动物中,IRS-2以脚手架蛋白发挥作用,协调胰岛素/IGF信号级联通路中的不同分支(2)。
Objective: to investigate plasma levels of insulin like growth factor 1 (IGF 1) and its binding protein 3 (IGFBP 3) in type 2 diabetes and their relationship with microangiopathy.
目的:观察2型糖尿病病人血中胰岛素样生长因子-1 (IGF - 1)及胰岛素样生长因子结合蛋白-3 (IGFBP - 3)水平与糖尿病及微血管病变的关系。
Objective To investigate the relationship between insulin-like growth factor-1(IGF-1)and type 2 diabetic macroangiopathy.
目的研究2型糖尿病大血管病变患者血清胰岛素样生长因子-1(IGF-1)水平变化及其临床意义。
Associations with 2-h glucose, insulin, and HOMA-IR remained significant after further adjustment for IGF-1, parathyroid hormone, calcium, physical activity, and social class.
经过进一步调整IGF - 1、甲状旁腺激素、钙、体力活动、和社会地位后,和2 -水合葡萄糖、胰岛素、HOMA - IR的联系仍然重要。
Associations with 2-h glucose, insulin, and HOMA-IR remained significant after further adjustment for IGF-1, parathyroid hormone, calcium, physical activity, and social class.
经过进一步调整IGF - 1、甲状旁腺激素、钙、体力活动、和社会地位后,和2 -水合葡萄糖、胰岛素、HOMA - IR的联系仍然重要。
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