Objective: To investigate the effects of high glucose and heparin on the proliferation and expression of MMP2, MMP9 in normal human mesangial cells (NHMC).
目的:研究高糖对正常人类系膜细胞(NHMC)增殖及金属蛋白酶2(MMP2)和金属蛋白酶9(MMP9)表达的影响及肝素对其的干预作用。
Conclusion: high glucose contributes to the increase of ICAM-1 expression in human mesangial cells. TPs can reduce high glucose-induced expression of ICAM-1.
结论:高糖可导致人肾小球系膜细胞ICAM - 1表达的增加,而茶多酚可有效干预此效应。
Objective To study the effects of high glucose on activity of mitogen activated protein kinase (MAPK) in cultured human mesangial cells and to explain the mechanism of diabetic nephropathy.
目的:研究高糖对人肾小球系膜细胞丝裂原蛋白激酶(MAPK)活性的影响,探讨其在糖尿病肾病发病中的作用。
Objective To study the expression of lipoprotein lipase(LPL) in human glomerular mesangial cells and the effect of very low-density lipoprotein(VLDL) on the expression of LPL.
目的探讨人肾小球系膜细胞脂蛋白脂酶(LPL)的表达情况以及极低密度脂蛋白(VLDL)对其表达的影响。
Methods Human glomerular mesangial cells were conventionally cultured.
方法人类系膜细胞常规培养。
Mesangial cell medium (MsCM) is a complete medium designed for optimal growth of normal human renal mesangial cells in vitro.
肾系膜细胞培养基是专门为正常人类肾系膜细胞体外培养设计的最适于其生长的培养基。
Mesangial cell medium (MsCM) is a complete medium designed for optimal growth of normal human renal mesangial cells in vitro.
肾系膜细胞培养基是专门为正常人类肾系膜细胞体外培养设计的最适于其生长的培养基。
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