The researchers genetically blocked ERBB3 in a mouse model of colon cancer and in human colon cancer cell lines.
研究者们从遗传上敲除了结肠癌鼠模型和人类结肠癌细胞系的ERBB3基因。
Objective To study the effect of RNA interference (RNAi) on HYAL1 gene mRNA expression and the invasive potential of human breast cancer cell lines.
目的研究rna干扰对透明质酸酶基因hyal1的表达以及对人乳腺癌细胞侵袭力的影响。
Because the oncogenes had been artificially introduced into those cell lines, the researchers then tested their model in human lung cancer cells with the EGFR mutation.
上述试验是人工将癌基因导入肿瘤细胞株,另外的实验是在具有EGFR突变的肺癌肿瘤模型上进行。
Objective to explore the expression and effects of isoforms of macrophage colony-stimulating factor in human leukemic cell lines.
目的探讨异型巨噬细胞集落刺激因子在人白血病细胞系中的表达和性质。
In the human colon cancer cell lines that are resistant to EGFR inhibitors, cell death increased dramatically when ERBB3 was genetically removed.
在人类对EGFR抑制因子耐药的结肠癌细胞系中,当ERBB3遗传学上被除去后,细胞死亡明显增加。
Nonhuman primates were phylogenetic closeness to human being and its ES cell lines are very similar to human.
非人灵长类作为与人类亲缘关系最密切的动物,其ES细胞与人类十分接近。
Objective: To study the effects of prokaryotically expressed recombinant human NDRG2 on tumor cell lines.
目的:考察原核表达的重组人NDRG2蛋白对肿瘤细胞的作用。
Objective To explore the relationship of chemotherapy sensitivity and expression of multidrug resistance genes and apoptosis regulation genes in human breast cancer cell lines.
目的探讨人乳腺癌细胞化疗敏感性与多药耐药相关基因和凋亡调控基因表达的关系。
ABSTRACT Objective to investigate susceptibilities of four human hepatoma cell lines to chemotherapeutics.
目的研究化疗药物对不同株人肝癌细胞杀伤作用的敏感性。
To establish stromal cell lines of human aorta-gonad-mesonephros (AGM) region and study the growth characteristics and hematopoiesis related molecules expression in these cells.
人AGM区基质细胞系呈现造血组织特异的相关分子表达特征,可以作为研究造血发生机理的模式细胞。
Objective to study the effect of curcumin on human esophageal cancer cell lines A549 proliferation and apoptosis.
目的探讨姜黄素对人食管癌a 549细胞增殖和细胞凋亡的影响。
Objective To explore the relationship of chemotherapy sensitivity and expression of multidrug resistance genes and apoptosis regulation genes in human lung cancer cell lines.
目的探讨人肺癌细胞株对化疗药物的敏感性与多药耐药相关基因和凋亡调控基因表达的关系。
Objective to compare gene expression profile of human hepatocellular carcinoma (HCC) cell lines with different metastatic potentials, so as to screen for metastasis-related genes.
目的比较不同转移潜能人肝癌细胞系的基因表达谱,寻找与癌转移相关的基因表达改变。
Selection of the feeder layer, medium, and supplemental cytokines and their roles in establishing and maintaining human ES and EG cell lines at present are illustrated in detail systematically.
详细系统地说明了迄今为止建立人胚胎干细胞系所需要的饲养层类型、培养基组成、添加细胞因子种类及其作用;
Conclusion T739 mouse bladder cancer cell lines and tumor-bear model expressing human MUC1 were successfully established for the development of tumor vaccines targeting MUC1.
结论建立稳定表达人MUC1T739小鼠膀胱癌细胞株和t739荷瘤小鼠模型,可用于肿瘤疫苗研究。
Ganglioside GM3 has been proved to be a physiological cell differentiation inducer in several human leukemia cell lines. However, the inducing differentiation mechanism of GM3 remains unclear.
神经节苷脂gm3作为一种促分化剂已在多个细胞瘤株模型中得到证实,但迄今为止其促分化的详细机制仍未阐明。
Objective To compare the proliferative responses to 11 types of human myelin compositions between T cell lines (TCL) induced by delipidated myelin and intact myelin in multiple sclerosis (MS).
目的比较神经髓鞘和脱脂神经髓鞘诱导多发性硬化(MS)T淋巴细胞系(TCL)对11种神经髓鞘成份的增殖反应。
The mechanisms of fumonisin-induced toxicity have not been clarified, human and animal cell lines can been used extensively to study its toxicity.
伏马菌素毒性作用机制尚未研究清楚,目前采用了广泛的细胞试验进行研究。
Objective To screen the genes differentially expressed in human renal cell carcinoma (RCC) cell lines using suppression subtractive hybridization (SSH).
目的应用抑制性消减杂交技术构建人肾癌差异表达基因文库并进行差异表达基因筛选。
Results CLLEGFP can infect various human derived cell lines and express EGFP.
结果CLLEGFP能够感染各种人源细胞并表达EGFP。
Conclusion: The cobra venom cytotoxin had a high cytotoxic activity on cultured human cancer cell lines.
结论:眼镜蛇毒细胞毒素对体外培养的人癌细胞有很强的杀伤作用。
Objective: Quantitative evaluation of cytotoxicity and sensitivity of taxol against human colorectal cancer cell lines.
目的:定量评价紫杉醇对人大肠癌细胞的杀伤作用和药物敏感性。
Methods The cytotoxic activity of LHRH-PE40 to the human tumor cell lines cultured in vitro was detected by MTT method, and sensitive tumor cell lines were selected out.
方法用MTT检恻LHRH-PE40对体外培养的人肿瘤细胞的细胞毒作用,找出敏感肿瘤细胞系。
Many different cells including porcine, human hepatocytes or cell lines have been used and different culture methods have been studied to optimize the activity of the biological component.
众多不同的细胞诸如猪肝、人肝细胞或细胞系均已应用,也研究了不同的培养方法,以期完善生物组分的活性。
Methods FCM and the zymography were used to study the human melanoma cell lines with different metastatic potential.
通过流式细胞术定量研究和蛋白酶活性分析,对具有不同潜在转移能力的人黑色素瘤细胞进行研究。
Some of them are active against some viruses, fungi and cancer cell lines, and harmless to human normal cells.
某些抗菌肽还具有抗病毒、抗真菌及抑制癌细胞生长的作用。
AIM: to investigate the inhibitory effects of recombinant human Mullerian inhibiting substance on cell proliferation in human ovarian carcinoma cells (OVCAR8 and SKOV3 cell lines).
目的:探讨重组人苗勒抑制物对人卵巢癌细胞株ovcar8及SKOV3细胞生长的影响。
AIM: to investigate the inhibitory effects of recombinant human Mullerian inhibiting substance on cell proliferation in human ovarian carcinoma cells (OVCAR8 and SKOV3 cell lines).
目的:探讨重组人苗勒抑制物对人卵巢癌细胞株ovcar8及SKOV3细胞生长的影响。
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