METHODS: Using CHO cells which high express human CD59 as target cells, the phage 12 peptide library was screened for 5 rounds by competitive binding test.
方法：以高表达人CD59的中国仓鼠卵巢细胞（CHO）为靶细胞，采用竞争结合试验，对噬菌体随机12肽库进行5轮亲和筛选。
AIM: To screen and identify the short-peptide which specifically bind to human CD59 so as to design short-peptide clamp with counteracting tumor escape activity.
目的：筛选并鉴定与人CD59分子特异结合的短肽，为设计具有拮抗CD59肿瘤逃逸活性的短肽封条奠定基础。
ObjectiveTo establish a cell model expressing human mutant CD59 molecular, and study its biological activities.
目的建立表达人突变CD59的细胞模型，初步研究其活性。
To construct human mutant CD59(HMCD59) eukaryot ic expression system and investigate whether glycation could inhibit the protection role of HMCD59 against human complement.
构建突变人CD59分子（HMCD59）真核表达体系，探讨HMCD59糖基化前后抗补体活性的变化。
To construct human mutant CD59(HMCD59) eukaryot ic expression system and investigate whether glycation could inhibit the protection role of HMCD59 against human complement.
构建突变人CD59分子（HMCD59）真核表达体系，探讨HMCD59糖基化前后抗补体活性的变化。
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