Cabamazepine treatment could induce a higher acetylation level of HSP90 and destroy its chaperon function.
卡马西平处理可以使HSP90乙酰化水平升高,并且破坏HSP90的分子伴侣功能。
Objective: To observe the effects of electroacupuncture on expression of HSP90 of myocardial ischemic area in rabbit heart.
目的:观察电针刺激对急性心肌缺血家兔心肌热休克蛋白90 (HSP90)表达的影响。
Objective To explore the function and mechanism of HSP90 in stress adaptation by construct HSP90 highly expressing cell lines.
目的建立HSP90稳定高表达细胞系,探讨HSP90在应激适应中的作用及其机制。
CONCLUSION: HSP70 and HSP90 are over-expressed in colon cancer, which are correlated with the biological behavior of colon cancer.
结论:结肠癌细胞存在HSP70和HSP90蛋白的过度表达,HSP70, HSP90和结肠癌细胞的生物学行为存在相关性。
Objective To investigate the correlation between the HSP90 expression and invasion and metastasis potential of human breast cancer cell line.
目的研究HSP90的表达与乳腺癌细胞侵袭转移能力的相关性。
Objective To probe the expression and role of the heat-shock protein 90 (HSP90) in the proliferation and differentiation of human brain gliomas.
目的探讨热休克蛋白90 (HSP90)在人脑恶性胶质瘤的表达及其在肿瘤增殖、分化中的作用。
P23, as one co-chaperone of HSP90, could bind to HSP90 specially, let HSP90 bind or release the target protein by regulating the form of the HSP90 binding with ATP or ADP.
此复合体中P23作为HSP90的伴侣分子,能够和HSP90特异性结合,调节HSP90与ATP或ADP结合的形式而达到结合或释放靶蛋白的功能。
HSP90 as a important member of HSP protein family, are usually constitutively expressed in most mammalian cell types and can be further induced by heat shock and other stresses.
HSP90是热激蛋白家族(hsp)的主要成员之一,它在细胞中呈高组成性表达,热激和其它应激条件可进一步诱导其表达。
HSP90 is an important member of HSP protein family. HSP90 usually constitutively expressed in most mammalian cell types and can be further induced by heat shock and other stresses.
HSP90是热激蛋白家族(hsp)的主要成员之一,它在细胞中呈高组成性表达,热激和其他应激条件可以进一步诱导其表达。
In fact, as a specific molecular chaperone, HSP90 proteins are possibly involved in many important physiological processes such as signal transduction, cell cycle regulation and hormone response.
事实证明,作为一种特异的分子伴侣,HSP90除在细胞正常生长和应急保护中具有重要生理功能外,还与信号传导、细胞周期调控、激素应答等细胞内重要生理过程有关。
Objective to explore the relationship between the expression of heat shock protein 90, 60 and 27 (HSP90, HSP60 and HSP27) and cell damage in peripheral blood of workers exposed to coke oven emissions.
目的探讨焦炉工外周血淋巴细胞热应激蛋白90、60及27 (HSP90、HSP60和HSP27)的表达水平及其与外周血细胞损伤之间的关系及意义。
Objective to explore the relationship between the expression of heat shock protein 90, 60 and 27 (HSP90, HSP60 and HSP27) and cell damage in peripheral blood of workers exposed to coke oven emissions.
目的探讨焦炉工外周血淋巴细胞热应激蛋白90、60及27 (HSP90、HSP60和HSP27)的表达水平及其与外周血细胞损伤之间的关系及意义。
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