纯合子是致命的。
In genetics, an allele that is expressed only in the homozygous state.
在基因学中，只有在同型结合的状态下才表现出来的一个等位基因。
F1 females could be backcrossed to the male homozygous recessive parent.
也可用雌性F1与隐性纯合雄性亲本回交。
Altogether, half the offspring will be homozygous at that particular locus.
加在一起，将有半数的后代在那个特定的位点上是纯合的。
Homozygous tetraploid is a relatively balanced system, the continued selection is invalid.
纯合的四倍体是一个相对平衡的系统，继续选择是无效的。
Objective: To study the pathogenesis of a homozygous patient with familial hypercholesterolemia.
目的：研究家族性高胆固醇血症纯合子患者的发病机理。
In genetics, refers to an allele that is expressed in both the heterozygous and homozygous condition.
指等位基因在杂合状态和纯合状态都有表达的现象。
Insect bioassay results showed that these homozygous lines had significant inhibition to brown planthopper.
抗虫鉴定结果发现这些纯系对褐飞虱具有明显的抑制作用。
Their newborn daughter died last year from a devastating dwarfism-related disease called homozygous achondroplasia.
他们的新生女儿去年死于一种破坏性很强的侏儒相关性疾病，叫做纯合软骨发育不良。
Results:In ALL, the incidence of P16 hypermethylation or homozygous deletion is 80%, there is no abnormal in control.
结果：AL LP16基因高度甲基化或纯合缺失发生率为80 % ，而对照组无一例P16基因失活；
The hybrid of parents that differ at only one gene locus, for which each parent is homozygous with a different allele.
杂交的双亲只有一个基因位置不同，对它来说，每个亲本是有一个不同的等位基因混合的。
Most plants carry a large genetic load for deleterious recessive genes of which a few are homozygous and depress growth.
多数植物带有大量有害的隐性基因的“遗传负荷”，其中少数是纯合的，因而降低了生长。
Homozygous mutant mice showed expected ratio and no obvious defect in sizes and morphologies at all embryonic stages examined.
纯合子突变小鼠在各个胚胎时期都有预期中的出现比例，在大小与型态上并没有明显的缺陷。
RESULTS: The final accuracy for homozygous and heterozygous single-nucleotide polymorphisms reached 99.62% and 98.39%, respectively.
结果显示，纯合子和杂合子的单核苷酸多态性的最终精度分别达到99.62%和98.39%。
Those pure lines derived from the homozygous diploids resemble routine inbred line in purity, genetic stability and combining ability.
经过鉴定证明这些纯系在纯度、遗传稳定性和配合力等方面均可以与常规自交系相比拟。
This locus occurs in over 40% of the population and is associated with increased risk of 40% in homozygous and 15 to 20% in heterozygous.
该位点出现在40%以上的人群中，其与纯合子风险增大40%以及杂合子风险增大20%的现象相关。
Children who were homozygous for the Arg16 allele and were exposed to two or more smokers had a 5-fold increased risk of lifetime wheeze.
Arg16等位基因纯合型的孩子同时家中有2个甚至更多的吸烟者的有多5倍的终生喘鸣的风险。
The two options available to us for treating children with very severe homozygous form of the disease are to one either perform LDL apheresis.
这两种选择可用于治疗儿童该病非常严重纯合子形式。方式之一是进行LDL单采。
The rate of homozygous deletion of Exon8 was 29.3%(12/41), and it was related to the tumor pathological grade, TNM stage and lymph node metastasis (P<0.05).
第8外显子纯合性缺失率为29.3%（12/41），且与患者TNM分期、病理分级及淋巴结转移有关（P<0.05）；
However, most (90%) of homozygous mutant mice die within 24 hours after birth, and 63% of them show severe air dilatation and lack milk in stomach and intestine.
然而大部分(90%)的纯合子突变小鼠都在出生后24小时以内陆续死亡。其中63%的肠胃都出现有严重的气体胀大与缺乏奶水。
On the one hand, searching for heterozygous variants can be slightly trickier, said Veltman, because individuals have many more heterozygous variants than homozygous.
一方面，Veltman表示，寻找杂合变异体要略微棘手一些，因为个体携带的杂合变异体比纯合变异体要多得多。
Results a homozygous mutation at exon 13 of the proband was found by parallel TGGE. Homozygous and heterozygous mutations were also found in the family by parallel TGGE.
结果平行tgge发现，两患儿第13外显子存在一纯合突变，其父母此外显子存在杂合突变。
The paper introduces the breeding methods of the homozygous two-type line, temporary maintainer line and complete sterile line with a recessive epistasis nuclear male sterile.
对甘蓝型油菜隐性上位细胞核雄性不育纯合两型系、临保系和全不育系的转育方法进行了介绍。
Instead of looking for homozygous variants where each parent carried an allele, the researchers were looking for heterozygous variants that were also not present in the parents.
研究人员寻找不存在与父母中的杂合变异体，而不是寻找每位亲本携带一个等位基因的纯合变异体。
The periportal red hyaline globules seen here with periodic acid-Schiff (PAS) stain are characteristic for alpha-1-antitrypsin deficiency (a person with homozygous pi-ZZ genotype).
过碘酸-雪夫（PAS）染色时，门脉周围的红色玻璃样小球是α-1-抗胰蛋白酶缺乏症（pi-ZZ纯合子基因型患者）的特征表现。
Heterozygous type I (quantitative) and most type II (qualitative) antithrombin deficiencies highly increase the risk of venous thromboembolism (VTE), while homozygous mutations are lethal.
杂合子i型(定量)和大多数II型(定性)抗凝血酶缺乏症使静脉血栓栓塞(VTE)的风险显着增加，而纯合型突变会导致死亡。
The haploid plant is the best material for genetic research of carrot, and homozygous diploid formed by doubling chromosome of the haploid plant is also the best resource of breed seed selection.
而单倍体植株是胡萝卜遗传研究的最好材料，由单倍体植株染色体加倍而成的纯合二倍体，又是品种选育的最好资 源。
The haploid plant is the best material for genetic research of carrot, and homozygous diploid formed by doubling chromosome of the haploid plant is also the best resource of breed seed selection.
而单倍体植株是胡萝卜遗传研究的最好材料，由单倍体植株染色体加倍而成的纯合二倍体，又是品种选育的最好资 源。
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