Methods HLA-B27 detection was made in 328 patients with AS, 1113 patients with waist-back-leg ache and 40 healthy individuals.
方法:应用流式细胞仪法对328例AS患者1、113例腰背腿疼患者和40例健康体检人员进行了HLA-B27抗原检测。
Flow cytometry was used to detect the expression level of HLA-B27 in peripheral blood of 45 cases with leukemia after Allo-PBSCT.
采用流式细胞术动态检测45例白血病患者异基因外周血干细胞移植前后人类白细胞抗原B27表达的变化。
Research the incidence of HLA-B27+AAU associated with AS and the relapse rate of AAU. offer the scientific foundation for the clinical diagnosis and treatment.
研究HLA-B27阳性AAU病例合并强直性脊柱炎(AS)的发生率,和AAU复发情况,为临床诊断和治疗提供科学依据。
Recently, self-antigens derived from collagen and non- arthritogenic proteins were demonstrated to bind to HLA-B27 molecule and cause specific T cell responses.
研究发现,来源于胶原蛋白以及非关节源性蛋白的自身抗原可引起特异性的T细胞反应。
Research about crystal structure of HLA-B27-peptide complexes suggested the specificity and plasticity of peptide-binding and subtypes dependent binding features.
对B27与抗原肽复合物晶体结构的研究表明,B27与抗原肽结合具有特异性和可塑性,不同亚型具有不同的结合特点。
OBJECTIVE: To explore the accuracy, sensitivity and specificity of IMS-ELISA for detecting HLA-B27 and its value in the auxiliary diagnosis of ankylosing spondylitis.
目的:了解磁珠酶联免疫分析法检测人类白细胞抗原-B27的准确性、敏感性和特异性,探讨其在强直性脊柱炎辅助诊断中的价值。
OBJECTIVE: To explore the accuracy, sensitivity and specificity of IMS-ELISA for detecting HLA-B27 and its value in the auxiliary diagnosis of ankylosing spondylitis.
目的:了解磁珠酶联免疫分析法检测人类白细胞抗原-B27的准确性、敏感性和特异性,探讨其在强直性脊柱炎辅助诊断中的价值。
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