Here's a video that animates the acetylation of histone proteins in the regulation of gene expression in cancer cells.
下面的视频是关于在癌症细胞里的常规基因表达是如何进行组蛋白乙酰化作用(acetylationofhistone)的。
Other work has focused on histone acetylation, a chemical modification that unwinds DNA from protein spools called histones, thereby enabling gene activity.
其他的工作集中在组蛋白乙酰化，这种化学修饰可以使DNA从组蛋白缠绕中解离出来，产生基因活性。
Histone is the core of chromatin, and covalent modification of histone tails have fundamental roles in regulation of gene expression.
组蛋白是染色质的核心，其尾部共价修饰在基因表达调控中有重要作用。
When methyl groups are added to a histone, they modify its properties and alter the frequency at which a particular gene is expressed.
当甲基加到组蛋白后，这些基团会修饰它的性质并改变它上面特定基因的表达频率。
Histone acetylation and deacetylation can regulate many chromosome functions, such as gene expression and chromosome segregation.
组蛋白乙酰化和去乙酰化可调节染色体的多种功能，例如基因表达和染色体分离等。
SATB1 also globally regulates histone status in the chromatin by recruiting histone-modifying enzymes to the target-gene loci.
在染色体中，SATB1还在靶基因位置上通过复活组蛋白修饰酶普遍的调节组蛋白的状态。
DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription, induce gene silencing at the participation of many regulators.
DNA甲基化由DNA甲基转移酶催化，在多种调节因子的参与下，与组蛋白修饰相互作用，抑制基因转录，导致基因沉默。
The methylation of histone H3-K27 was proved to be linked to several silencing phenomena including homeotic-gene silencing, X inactivation and genomic imprinting.
组蛋白H3第27位赖氨酸的甲基化与同源盒基因沉默、X染色体失活、基因印记等基因沉默现象有关；
The acetylation of histone is related to gene expression and regulation, which takes part in the pathological courses of all kinds of lung diseases.
组蛋白乙酰化修饰与基因的表达调控相关，参与了各种肺部疾病的病变过程。
Histone acetylation and de-acetylation can change the structure of chromatin, involving in gene expression regulation and nuclear reprogramming.
组蛋白乙酰化和去乙酰化可以改变染色质的结构，参与基因的表达调控和重编程。
Histone modifications are implicated in influencing gene expression.
蛋白修饰与影响基因表达有关。
Combined with the results of histone deactylase inhibitor, it is suggested that histone acetylation plays an important role in hsp gene transcription regulation.
结合以上去乙酞化酶抑制剂的实验结果，我们认为组蛋白乙酞化修饰参与了热休克基因的表达调控。
The role of histone lysine methylation in the gene expression regulation has turned into the hotspot of epigenetics.
组蛋白赖氨酸甲基化在基因表达调控中的作用已成为表观遗传学研究的热点。
These alterations in the histone code may alter gene expression pattern to set the stage for leukemogenesis.
组蛋白密码的这些改变可能改变基因表达模式以设定白血病发生状态。
The invention belongs to the technical field of plant gene engineering, and more particularly relates to a paddy rice histone demethyl methylase gene, coded protein and the application thereof.
本发明属于植物基因工程技术领域，具体涉及一种水稻组蛋白去甲基化酶基因及其编码蛋白与应用。
This study identifies the major deubiquitinase for histone H2A and demonstrates that H2A deubiquitination is critically involved in cell cycle progression and gene expression.
本研究确定了主要的组蛋白h 2 A去泛素和表明H2A去泛素化是至关重要参与细胞周期进程和基因表达。
Histone acetylation has a close relation with some biological effects such as gene transcription, and is catalyzed by histone acetyltransferases.
组蛋白乙酰化与基因转录等生物效应有密切的关系，组蛋白乙酰化主要是由组蛋白乙酸转移酶催化的。
In this paper, we reviewed the mechanisms on histone acetyltransferases regulating gene transcription and histone deacetylase inhibitors promoting memory formation.
本文主要就组蛋白乙酰转移酶调节基因转录以及组蛋白去乙酰化酶抑制剂促进记忆形成的作用机理进行综述。
Histone deacetylase inhibitors increase the acetylation level of histone as well as some non-histone proteins, and specifically modulate some gene expression.
组蛋白去乙酰酶抑制剂可提高组蛋白的乙酰化水平，并对一些非组蛋白成分产生影响，从而调节某些特定基因的表达。
Histone acetylation contributes to expression of gene, while histone deacetylation leads to repression of gene expression.
组蛋白乙酰化促进基因表达，而去乙酰化则抑制基因表达。
The "histone code" is comprised of the covalent modifications of histone tails that function to regulate gene transcription.
“组蛋白密码”是由起调控基因转录功能的组蛋白末端的共价修饰所组成。
The "histone code" is comprised of the covalent modifications of histone tails that function to regulate gene transcription.
“组蛋白密码”是由起调控基因转录功能的组蛋白末端的共价修饰所组成。
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