Methods BALB/c mice were immunized by subcutaneous injection of polypeptides from HCV core region, and the CTL activity of mouse spleen cells was detected by the LDH release test.
方法将HCV核心区多肽皮下注射免疫BALB/c小鼠,用乳酸脱氢酶释放实验检测小鼠脾细胞CTL活性。
Peripheral T-lymphocyte subsets of 48 HCV-RNA seropositive and 35 HCV-RNA seronegative chronic hepatitis -C patients were investigated arid 20 normal subjects were kept as control.
对48例血清HCV-RNA阳性和35例HCV-RNA阴性的慢性丙型肝炎(慢丙肝)患者外周血T淋巴细胞亚群进行观察,并与20例正常人对照。
Objective:To detect whether hepatitis B virus(HBV) and hepatitis C virus(HCV) could infect the same host cell.
探索乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)是否可同时感染同一宿主细胞。
It is significance to explore the role in chronicity of extra-hepatic cells, especially peripheral blood mononuclear cells (PBMC) with HCV infection in hepatitis c.
进一步探讨肝外细胞尤其外周单个核细胞(PBMC)的HCV感染对丙型肝炎慢性化有重要意义。
Methods: Immunohistochemical assay was used to determine the expression of HCV antigen in the kidneys, heart, pancreas, intestine and liver in 9 patients with viral hepatitis c.
方法:采用免疫组化法检测9例丙型肝炎患者肾、心、胰和肠等肝外组织内hcv抗原,并与肝组织内抗原表达进行对比研究。
Objective To explore the state of extrahepatic hepatitis C virus (HCV) infection, viral pathogenicity and its significance in hepatitis C patients.
目的探讨丙型肝炎患者肝外组织丙型肝炎病毒(HCV)感染状态、致病性及其意义。
Objective To find neutralizing antibody candidates against hepatitis C virus (HCV) infection.
目的寻找可能存在的抗丙型肝炎病毒(HCV)感染的中和抗体。
The cases with hepatitis C were confirmed by various serological tests including tests for anti-HCV antibodies and PCR for HCV RNA.
所有丙型肝炎病例均经多项血清学检查(包括HCV抗体的检测,应用PCR 技术检测HCV RNA 等)证实。
Objective To study the association of the envelope region variation of hepatitis C virus (HCV) with the chronicity of HCV infection.
目的探讨丙型肝炎病毒(HCV)包膜区变异与其感染慢性化的关系。
The different genotypes of HCV were related to the severity of hepatitis C.
HCV基因型与丙型肝炎严重程度密切相关。
Background Patients with genotype 1 hepatitis C virus (HCV) who do not have a sustained response to therapy with peginterferon alfa and ribavirin have a low likelihood of success with retreatment.
背景有基因1型丙型肝炎病毒(HCV)感染,但对聚乙二醇干扰素α和利巴韦林疗法没有持续应答的病人,复治成功的可能性低。
Non-structural protein 3(NS3) of hepatitis C virus (HCV), the serine protease, is a key functional protein, which is responsible for the processing of HCV polyprotein.
利用毕赤酵母系统表达具有催化活性的丙型肝炎病毒(HCV)NS3蛋白酶。
Nowadays, several epidemiologic studies have confirmed the link between hepatitis C virus(HCV) infection and diabetes mellitus, which is more obvious in those patients overweight or with an old age.
近年来,有很多流行病学调查证实了H CV感染与糖尿病的关联,这种关联在年龄大、体重超标的患者身上表现更为明显。
Objective To investigate mother to child transmission ofhepatitis C virus (HCV) and the influence of HCV infection on the physical development of newborns.
目的了解丙型肝炎病毒(HCV)母婴垂直传播情况及HCV感染后对新生儿体格发育的影响。
Background & Aims: Broadly reactive neutralizing antibodies (nAbs) and multispecific T-cell responses are generated during chronic hepatitis C virus (HCV) infection and yet fail to clear the virus.
背景和目的:慢性HCV感染过程中能够产生广泛的中和性抗体(nAbs)和多特异性的T细胞反应,但仍然不能够清除病毒。
Objective To investigate the clinical application of detecting hepatitis C virus ribonucleic acid (HCV RNA) using various number of serum samples from patients planning to receive blood transfusion.
目的探讨不同数量混合血清样本丙肝病毒核酸(HCVRNA)检测在拟输血手术患者中的临床应用。
Some more modern new drugs that provide some support in treating HCV are Albuferon, Zadaxin,. Antisense phosphorothioate oligos have been targeted to hepatitis C.
更多的支持治疗HCV的新药品是Albuferon、日达仙,反义的磷酸寡核苷酸已经用来治疗丙型肝炎。
Objective To study the immunogenicity of multiple antigen peptide (MAP) corresponding to the hypervariable region 1(HVR1) within the putative envelope glycoprotein E2/NS1 of hepatitis C virus(HCV).
目的应用多抗原肽(MAP)研究丙型肝炎病毒包膜糖蛋白高变区1(HVR1)的抗原性。
Objective To study the immunogenicity of multiple antigen peptide (MAP) corresponding to the hypervariable region 1(HVR1) within the putative envelope glycoprotein E2/NS1 of hepatitis C virus(HCV).
目的应用多抗原肽(MAP)研究丙型肝炎病毒包膜糖蛋白高变区1(HVR1)的抗原性。
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