Objective: To study the relationship between PTEN expression and HCV core protein in hepatocellular carcinoma (HCC).
目的：研究抑癌基因PTEN在人肝细胞肝癌中的表达及其与HCV核心蛋白间的关系。
Understanding the molecule mechanisms of HCV core protein induction hepatic steatosis may contribute to elucidate the etiology, prevention and treatment of HCV hepatic diseases.
了解hCV核心蛋白在诱发肝脂肪变性中的分子学机制，对丙型肝炎相关性脂肪肝的病因学，预防和治疗等方面具有极大的促进作用。
CONCLUSION: Yeast two-hybrid GAL4 system 3 can be utilized to fish HCV core region-interacting protein. HCV core protein does not have self-activating function.
结论利用酵母双杂交Gal4系统3研究与HCV核心蛋白相互作用的蛋白，证实了HCV核心蛋白无自激活功能。
In addition, the ratio of anti-E antibody in HCV core protein antibody positive sera was lower than that of RNA positive ones.
其中，抗HCV核心抗体阳性的血清中抗E抗体检出率低于RNA阳性血清中抗E抗体的检出率。
Methods BALB/c mice were immunized by subcutaneous injection of polypeptides from HCV core region, and the CTL activity of mouse spleen cells was detected by the LDH release test.
方法将HCV核心区多肽皮下注射免疫BALB/c小鼠，用乳酸脱氢酶释放实验检测小鼠脾细胞CTL活性。
Objective To evaluate the performances of HCV core antigen(HCV-cAg)testing in comparison to HCV RNA and Anti-HCV detection during the preseroconversion period.
目的探讨丙型肝炎病毒（HCV）核心抗原酶联免疫诊断试剂检测早期HCV感染“窗口期”样本的可行性。
Among HCV encoding gene, core region shows greater sequence conservation. Core gene expression has favorable antigen stability.
在HCV的编码基因中，核心区(C区)序列具有高度遗传保守性，c基因表达产物具有良好的抗原稳定性。
Objective To study the variation of HCV 5 '- NCR and core gene in serial sera collected from patients with HCV infection.
目的研究丙型肝炎病人的系列说清中HCV5'-NCR及核心区基因变化。
Results: There are some t and B cell epitopes on HCV core protein, and HCV core protein can affect cell cycle.
结果：综述了丙型肝炎病毒核心蛋白t、b细胞表位及对细胞周期的影响。
AIM: to construct the recombinant plasmids expressing full-length HCV core protein gene and 3 different deletion mutated hepatitis core protein genes and to express them in E. coli.
目的：构建丙型肝炎病毒(HCV)全长及3种不同缺失突变的核心蛋白基因的原核表达载体，并在大肠杆菌中表达。
Methods Serial sera were collected from 4 plasma-donors with HCV infection. 5' - NCR and core gene were amplified, sequenced and analyzed using software.
方法4例因献血感染HCV病人的系列血标本，用特异性引物扩增5'-NCR和核心区基因并进行测序。
ObjectiveAs plasmid with HCV core gene induces only very weak immune responses, enhancement of immune responses by cytokines can be beneficial to HCV vaccine.
目的HCV C蛋白基因诱导的免疫应答较弱，因而增强HCV C蛋白基因免疫对于开发HCV疫苗具有极其的重要性。
ObjectiveAs plasmid with HCV core gene induces only very weak immune responses, enhancement of immune responses by cytokines can be beneficial to HCV vaccine.
目的HCV C蛋白基因诱导的免疫应答较弱，因而增强HCV C蛋白基因免疫对于开发HCV疫苗具有极其的重要性。
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