Liver damage is probably associated with body immunity. HBV mutation maybe play a secondary role in Liver damage.
肝损伤可能主要与机体免疫等相关，HBV变异仅起次要作用。
ObjectiveTo study clinical meaning of new DNA chip technique in detecting the mutation of HBV-DNA , and to offer testimony for clinical diagnosis and treatment.
应用新型基因芯片研究乙肝病毒多点基因变异在慢性乙肝患者中的意义，为临床诊断和治疗提供依据。
Objective: To discuss mannose binding lectin (MBL) gene polymorphisms at 54 locus of Han population in Ningxia for further research on relationship of MBL gene mutation and HBV infection.
目的：探讨宁夏汉族人群中甘露糖结合凝集素(MBL)基因54位点多态性，为进一步研究MBL基因突变与乙型肝炎间的关联性提供依据。
Objective:To analysis the effects of HBV pre-C mutation in hepatic fibrosis and discuss the relationship of hepatic fibrosis and nitric oxide.
目的：分析乙型肝炎病毒（HBV）前C区基因变异在肝纤维化形成中的作用，探讨肝纤维化与一氧化氮的关系。
Objective To investigate the relationship of HBV Lumivudine resistant and HBV genotypes and basic core promoter (BCP) mutation.
目的了解拉米夫定耐药与HBV基因型及HBV基本核心启动子(BCP)突变之间的关系。
Objective To study clinical significance of DNA chip technique in detecting the mutation of HBV-DNA ORF, and to offer testimony for clinical diagnosis and treatment.
目的应用新型基因芯片研究乙肝病毒多点基因变异在慢性乙肝患者中的意义，为临床诊断和治疗提供依据。
To set up using the gene chip technology to detect and identify quickly and accurately the HBV P gene YMDD Motif mutation during the chronic hepatitis treated with lamivudine.
建立乙型肝炎病毒变异基因诊断芯片对拉米夫定治疗慢性乙型肝炎过程中出现的肝炎病毒P基因区YMDD变异进行快速准确的检测方法。
Conclusions the gene chip technique is simple to perform and can be used as a rapid and high-throughput method. It has a high clinical value in detecting the HBV gene mutation.
结论基因芯片技术检测HBV变异具有高通量、高灵敏等特点，对观察h BV基因突变有很高的临床应用价值。
Objective:To study distribution rule of HBV gene mutation sites in chronical hepatitis B with Yin deficiency of liver and kidney syndrome.
目的：研究慢性乙型肝炎肝肾阴虚证HBV基因突变点的分布规律。
Objective To study clinical meaning of DNA chip technique in detecting the mutation of HBV-DNA ORF, and to offer testimony for clinical diagnosis and treatment.
目的研究HBV-DNA多点基因变异在慢性乙肝中的临床意义，为临床诊断和治疗提供依据。
To study mechanism of relationship HBV gene mutation in chronic hepatitis B patients with TCM syndrome.
研究慢性乙型肝炎患者HBV前C区基因变异的变化规律与中医证候的相关机制。
Eligible patients were hepatitis B surface antigen-positive men and women with compensated liver disease who were given lamivudine at least more than 6 months and had HBV polymerase gene mutation.
符合条件的患者乙肝表面抗原阳性的代偿性肝脏疾病的男性和女性谁是至少6个月以上的，给予拉米夫定和HBV聚合酶基因突变。
HBV gene mutation along different types of TCM syndrome are detected by microarray assay.
基因芯片检测慢性乙型肝炎不同证候的HBV前C区基因变异。
Some gene position's mutation might have association with the HBV intrauterine infection.
本研究从HBV基因突变入手，进一步探讨可能与宫内感染发生有关的突变位点。
Conclusions During lamivudine therapy, there is no relation between the YMDD mutation and the HBV genotypes.
结论拉米夫定治疗期间，HBV的YMDD变异不受病毒基因型的影响。
HBV infection may be a positive risk factor for alcoholic liver disease. However, little is still known about the relationship between HBV gene mutation and habitual alcohol intake.
同时探讨了乙肝病毒感染对酒精性肝病易感性的影响，证实乙肝病毒感染是酒精性肝病的正性危险因素，但目前关于酒精对乙肝病毒变异影响的研究较少。
Methods the serum YMDD mutation, HBV DNA, ALT and HbeAg levels of 60 patients on lamivudine therapy were detected by FQ-PCR, ELISA, and rate method, respectively.
方法采用实时荧光定量pcr、ELISA及速率法分别检测60例乙肝患者经拉米呋啶治疗后其血清YMDD、HBVDNA、乙肝标志物及alt的变化情况。
Methods the serum YMDD mutation, HBV DNA, ALT and HbeAg levels of 60 patients on lamivudine therapy were detected by FQ-PCR, ELISA, and rate method, respectively.
方法采用实时荧光定量pcr、ELISA及速率法分别检测60例乙肝患者经拉米呋啶治疗后其血清YMDD、HBVDNA、乙肝标志物及alt的变化情况。
应用推荐