Listening to loud noise for a long time can cause some hair cells in the inner ear to die.
长时间听巨大的噪音会导致内耳的一些毛细胞死亡。
Hair cells, which took their name because under the microscope they look like cells with little hairs growing out of them, are an essential link in hearing.
内耳中的这种细胞是人类听觉不可或缺的一环。之所以称为“毛细胞”,是因为它们在显微镜下看上去就像是在细胞外长出了绒毛。
Researchers hope their work can unlock secrets to protect human hair cells from becoming damaged and to stimulate the cells to regenerate.
研究人员希望他们的工作可以揭开谜底,保护人类的毛细胞免受损伤、并推动毛细胞的再生。
More importantly, further study showed that the cells also responded to mechanical stimulation by producing currents just like hair cells.
更重要的是,进一步研究表明这些细胞和毛细胞一样,对电流引发的机械刺激又所回应。
Often, the reason is damage to specialised sensory cells known as hair cells.
通常认为原因是特殊感觉器官毛细胞受到了损伤。
Those chemicals found to confer protection on fish hair cells are currently also being tested on mice and rats.
研究人员目前还在老鼠身上试验那些对鱼类毛细胞有保护作用的化学物质。
Surrounding cells known as support cells can both turn into hair cells or generate new hair cells.
毛细胞周围的细胞被称为“支持细胞”,它们可以转化成毛细胞或者产生新的毛细胞。
And this means that the yellow cells on the right side are mouse hair cells in a chicken inner ear.
也就是说,右边黄色部分,代表的是小鸡内耳中的老鼠细胞。
That is because the treatment only caused the regrowth of a group of cells called the inner hair cells.
因为治疗仅仅引起了称为内耳毛细胞的细胞群的再生长。
Bernstein says Latisse in fact does work because it is changing the molecular structure of the hair cells.
Bernstein说事实上,Latisse能够起作用,是因为它改变了头发细胞的分子结构。
The hope was that the Math1 gene would be activated in the infected cells, which would then grow cilia, thus becoming hair cells.
寄希望于Math1基因能够在受感染的细胞中存活,产生纤毛,进而成为毛细胞。
In these experiments, which have yet to be published, he USES an antibiotic injection to knock out the hair cells devoted to balance.
他在这些尚在整理出版的试验中,使用了一种抗生素注射剂来破坏保持平衡的毛细胞。
To restore hearing, researchers still have to figure out how to produce millions of hair cells, prevent stem cells from forming tumors, and translate the work to human cells.
为了重建听力,科学家们还必须研究出如何大量生产毛细胞,如何避免干细胞形成肿瘤,以及如何应用于人类的细胞。
While researchers will ultimately need human hair cells, the mouse version is a good model for the initial phases of experimentation, he said.
他还说,小鼠细胞在研究初期是相当好的实验对象,但研究者们终将需要人类毛细胞来研究。
When the bundles were mechanically stimulated with a slender piece of glass, the cells generated electrical currents that resemble those produced by young hair cells.
当这些细胞束遇到了细小玻璃片的机械撞击,他们将产生与年轻毛细胞相似的电子流。
The method of creating hair cells in a dish will also allow scientists to discover molecules that enable hearing. And it will offer a way to screen for drugs that spur the growth of new hair cells.
在培养皿中制造毛细胞的方法将有助于科学家们发现促进听力的分子,也可用于刺激新的毛细胞生长的药物研发。
One of the roadblocks to understanding the molecular basis of hearing is the paucity of hair cells available for study, Heller said.
赫勒声称,由于用于研究的毛细胞数量稀缺,从而阻碍了他们进一步了解听觉的分子基础。
In this experiment, zebrafish are exposed to a dye that highlights living hair cells.
在他们的实验中,斑马鱼身上活的毛细胞被染色。
The inner ear contains tiny hair cells that deform when sound waves hit them.
内耳含有声波撞击即可变形的纤细的毛细胞。
A second group, the outer hair cells, did not reappear.
第二个细胞群,外耳细胞群并没有再现。
They were treated with antibiotics, to kill their hair cells. This made them completely deaf.
给它们施加抗生素来杀死毛细胞,使其完全耳聋。
Particularly if you compare them with hair cells that are present in the mammalian and the human and mouse cochlea.
尤其是与哺乳动物如人和老鼠的,耳蜗中的毛细胞相比。
The lab's research into the regeneration of hair cells for transplantation into the inner ear to cure deafness will also continue.
这项治愈耳聋的内耳毛细胞再生移植研究将继续下去。
There are two main approaches to efforts aimed at inducing hair cells to regenerate.
促进毛细胞再生主要有两种办法。
Heller's team treated cells taken from mouse embryos with various signaling molecules that coaxed them into becoming cells that looked and functioned like normal hair cells.
Heller的团队使用多种信号分子来诱导鼠胚胎来源的细胞分化为形态和功能与正常毛细胞相似的细胞。
This was a huge number for me up until 2 weeks ago Besides the 100 billion neurons in the brain. There are 12-15 thousand cochlear hair cells.
直到两周前,这对我来说还是个庞大的数字,除了这一兆亿个神经元外,还有12,000到15,000个毛细胞。
This was a huge number for me up until 2 weeks ago Besides the 100 billion neurons in the brain. There are 12-15 thousand cochlear hair cells.
直到两周前,这对我来说还是个庞大的数字,除了这一兆亿个神经元外,还有12,000到15,000个毛细胞。
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