GSTT1 -null is no correlated with the susceptibility of colorectal cancer.
GSTT1空白基因型与结直肠癌易感性无关。
It has been reported that GSTM1, GSTT1 genetic polymorphisms are associated with several malignancies.
据报道,GSTM1、GSTT1基因多态性与多种恶性肿瘤的发生密切相关。
Methods The genotypes of GSTM1 and GSTT1 of 63 cases with HCC and 88 controls were detected with multiple PCR technique.
方法应用多重PCR技术检测63例肝癌患者和88例健康对照的GSTM1和GSTT1空白基因型。
Objective to study the relationship between the null genotypes of GSTM1 and GSTT1 and the genetic susceptibility to HCC.
目的谷胱甘肽- S -转移酶m 1和t1 (GSTM1和GSTT1)空白基因型与肝癌遗传易感性的关系。
Conclusion: There is a synergy of susceptible genotypes GSTM1(0/0) and GSTT1(0/0) to enhance the individual susceptibility to chronic severe periodontitis.
结论:在内蒙古汉族人群中,基因型GSTT1(0/0)和GSTM1(0/0)增加了个体对重度慢性牙周炎易感性,且上述两种基因型间存在协同作用。
ObjectiveTo investigate the relationship of GSTM1 and GSTT1 gene polymorphisms with the development of noise induced hearing loss (NIHL) in Chinese workers.
目的探讨谷胱甘肽硫转移酶M1和T1(GSTM1和GSTT1)的基因多态性与噪声性听力损失易感性之间的关系。
Objective To investigate the distribution of glutathione-S-transferase T1(GSTT1) gene polymorphism in health Yao and Han nationalities of guangdong province.
目的探讨广东地区瑶族和汉族健康人群谷胱甘肽硫转移酶T1(GSTT1)基因多态性的分布。
Objective In order to examine the relationship between glutathiones transferase M1, T1(GSTM1, GSTT1)genetic polymorphism and susceptibility to gastric cancer.
目的探讨谷胱甘肽转硫酶M1(GSTM1)、T1(GSTT1)基因多态性与胃癌遗传易感性的关系。
Associated significantly in the genes polymorphisms of GSTM1 and GSTT1 with asthma bronchial, their genes mutation may be the genetic risk factor of asthma bronchial.
提示GSTM1和GSTT1基因多态性与哮喘有显著性关联,两个基因的突变可以被视为发生支气管哮喘遗传风险因子。
Objective to examine the relationship of genetic polymorphisms of glutathione S-transferase (GST) including GSTM1 and GSTT1 and the susceptibility to childhood leukemia.
探讨谷胱甘肽s转移酶m 1 (GSTM1)和T1 (GSTT1)基因多态性与儿童白血病遗传易感性的关系。
Conclusion GSTM1 deletion may be an important host risk for lung cancer in nonsmoking women, whereas GSTT1 deletion is not associated with the risk to lung cancer in women.
结论GSTM1基因缺陷型可能是非吸烟女性患肺癌的重要危险因素,GSTT1基因缺失则可能与肺癌的发生无关。
Objective To explore the association between the null genotypes of GSTM1 and GSTT1 and the genetic susceptibility of primary liver cancer(PLC) in the low-incidence area of PLC.
目的探讨肝癌低发区谷胱甘肽转硫酶(GST)M1和T1的缺失基因型与肝癌的关系。
The objective of this study is to investigate the relationship between genetic polymorphism of GSTT1 and inherent susceptibility to lung cancer in Han population in Sichuan, China.
本研究的目的是探讨GSTT1基因多态性与中国四川汉族人群肺癌遗传易感性的关系。
The frequencies of GSTM1-null and GSTT1-null genotypes in colorectal tumor and control groups were ascertained by using polymerase chain reaction (PCR) and multiple-PCR techniques.
应用聚合酶链式反应(PCR)、多重PCR方法检测GSTM1和GSTT1在正常人群和结直肠肿瘤患者群体中的基因多态性分布。
Mehtods a case control study was carried out and polymerase chain reaction (PCR) technique was used to identify GSTM1, GSTT1 genotype in 89 cases of primary gastric cancer and 94 controls.
方法采用病例对照分子流行病学研究方法和聚合酶链反应技术,检测89例原发性胃癌病例和94例对照GSTM 1和GSTT1基因型。
Smoking and drinking habit are likely associated with the susceptibility to gastric cancer; interaction of GSTM1, GSTT1 genotype and smoking, alcohol drinking exists in the risk of gastric cancer.
吸烟、饮酒与胃癌易感性增加有关,GSTM1和GSTT1基因型及烟酒嗜好在胃癌发生中存在一定的交互作用。
Smoking and drinking habit are likely associated with the susceptibility to gastric cancer; interaction of GSTM1, GSTT1 genotype and smoking, alcohol drinking exists in the risk of gastric cancer.
吸烟、饮酒与胃癌易感性增加有关,GSTM1和GSTT1基因型及烟酒嗜好在胃癌发生中存在一定的交互作用。
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