Defects in DNA damage response can cause genome instability, which induces many human cancers.
DNA损伤反应机制的任何功能缺陷将会引起基因组的不稳定性，从而导致癌症的发生。
The instability of genome which results from defect of MMR genes is thought as a new oncogenesis way.
由于错配修复基因缺陷而导致的基因组不稳定，被认为是导致肿瘤发生的一条新途径。
The instability of genome which results from defect of MMR genes is thought as a new oncogenesis way.
由于错配修复基因缺陷而导致的基因组不稳定，被认为是导致肿瘤发生的一条新途径。
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