And it is here that the new generation of genome-wide tests comes in.
这正是新一代的全基因组测试的切入点。
At the moment, most of the studies are genome-wide association studies.
目前,多数研究是全基因组关联研究。
Cancer risk in chronic hepatitis B: Do genome-wide association studies hit the mark?
慢性乙肝的癌症风险:全基因组协会研究达到目的了吗?
Through seriate genome-wide mRNA expression data, similarity between two genes could be measured.
通过分析酵母细胞的大规模基因表达谱数据,获得不同基因间表达的相关性。
The discovery was made with a technique called a "genome-wide scan," which is only a few years old.
这个发现得益于一项几年前刚出现的名为“基因组扫描”的技术。
It turns out that while Laszlo and Cassandra's genome-wide comparison is 83.82% similar, he and I are 83.95% alike.
事实证明,儿子和卡桑德拉的基因组对比有83.82%的相似度,但他和我的相似度却是83.95%。
Microarray experiments are providing unprecedented quantities of genome-wide data on gene-expression patterns.
微阵列实验的全基因组基因表达模式的数据提供了前所未有的数量。
It turns out that while Laszlo and Cassandra's genome-wide comparison is 83.82% similar, heand I are 83.95% alike.
事实证明,儿子和卡桑德拉的基因组对比有83.82%的相似度,但他和我的相似度却是83.95%。
The [new] study is small relative to the previous genome-wide association studies of coffee consumption, Cornelis said.
康奈利说:“新的研究和之前的全组基因与咖啡消费行为的研究相关甚微。”
The function analysis of Large genome-wide data needs new algorithm, software, and the strong support of the computing platform.
大规模的全基因组数据的功能分析需要新的算法、软件和强大的计算平台的支持。
Objective to identify genes associated with hepatocellular carcinoma (HCC) as candidate diagnostic markers in a genome-wide scale.
目的在全基因组范围内筛选肝细胞癌候选诊断指标。
In this study, system analysis of substrate spectra of predicted sugar transporters in N. crassa was performed at genome-wide level.
本研究从全基因组水平系统分析了粗糙脉孢菌预测糖转运蛋白的转运底物。
The classic approach to determining linkage of a complex trait has involved the technique of genome-wide scanning with microsatellites.
检测复杂性状连锁的经典方法与全基因组与微卫星扫描法相关。
Right now, we are not in a position to use genome-wide associations or even selected genome scans for common variants to prognosticate.
目前,我们尚无法通过对应用基因组或甚至选定基因进行常见变异的检查来进行预测。
Conclusions:The HPLC method that we have established for assaying the genome-wide DNA total methylation level is stable and reproducible;
结论:本文所建立的高效液相色谱法能够准确灵敏地检测全基因组总体甲基化水平,检测结果稳定,方法重现性好;
The database contains the information on disruption phenotypes, gene expression, and protein localization on a genome-wide scale in Saccharomyces.
数据库中包括转座以后表型的改变,基因表达和酵母 基因组水平蛋白的定位等数据。
The main course, however, is provided by three opinion pieces tackling the recent results of genome-wide association studies from quite different angles.
但主题来自于从不同角度对基因组相关性研究结果处理时产生的三种意见。
He added, “We have literally hundreds of genome-wide association studies for common diseases, and in most cases we are having trouble making much use of them.”
他补充说,“我们已经进行了许许多多的泛基因组研究,但是在大多数事例中,应用他们的时候都遇到了很多麻烦。”
We now have such tools as neuroimaging and genome-wide scans that hunt for genes related to risk, as well as big samples of people who've been followed over time.
我们现在已经有了像神经成像和全基因组扫描那样的工具来搜寻与阿尔茨海默氏症有关的基因,以及经一大批经过长时间随访的人群样本。
The output of genome-wide association studies is vast, yet it is rarely straightforward to identify the functional connection between a variant and a disorder.
全基因组学关联研究所产生的数据结果是巨大的,但是很少能直接鉴别出突变和病症之间的功能关系。
MOTIVATION: Gene expression analysis with microarrays has become one of the most widely used high-throughput methods for gathering genome-wide functional data.
动机:用微阵列进行基因表达分析已经成为收集全基因组功能数据的最广泛使用的高通量方法之一。
Recent advances in technology make it possible to perform large-scale, genome-wide interaction mapping experiments that result in an always increasing amount of data.
技术中的最新进展使得执行大规模、全基因组相互作用图谱实验成为可能,这导致了一直在增加的数据量。
The present invention relates to osteoarthritis (OA) and methods of OA diagnosis and treatment via the findings of a genome-wide analysis of dysregulated genes in OA.
通过对基因库的分析而发现骨关节病变组织中非正常表达的基因,可作为早期诊断的生物标记。
Researchers at Johns Hopkins University and the University of Illinois at Chicago used genome-wide screening techniques on families that had two or more children with autism.
约翰·霍普金斯大学和芝加哥伊利诺州大学的研究人员采用基因筛选技术对有两个或多个自闭症孩子的家庭进行了研究。
In the case of high blood pressure, for instance, large genome-wide studies have thus far found no common variants that are associated with the risk of developing hypertension.
而对于高血压来说,大型基因组范围研究还未发现与高血压发病风险相关联的普通变异。
"We have a road map for this as the first 'killer app' for genome engineering, which is to change the genetic code genome-wide to something that the viruses don't expect," he says.
“我们为此制作了路线图,作为基因工程的第一个‘杀手程序’,它将对基因密码进行重大改变,使病毒无法预测和识别,”他说道。
As striking as these images were, they could be seen as more art than science, because systematic genome-wide sequencing had yet to be applied to individuals for medical purposes.
这些图片是如此引人注目,它们可能被更多地看作是艺术而非科学,因为系统的全基因组测序还没有以医学为目的应用到个体上。
Currently, several approaches have been developed for gene enrichment on a genome-wide scale, such as cDNA library, methylation filtration library, high Cot library and transposon tagging.
目前,在基因组范围内富集基因的方法有cD NA文库、甲基化过滤文库、高Cot值文库、转座子标签富集法等。
Along with colleagues in Iceland, Switzerland and the Netherlands, the researchers conducted a genome-wide association study of 1,125 Caucasian men who had been assessed for male pattern baldness.
在冰岛,瑞士和荷兰的同事的协助下,研究人员对1125名患有男性型秃发的白人男子进行了全基因组关联研究。
Progress in understanding the genetic basis of atherosclerosis has come both from genome-wide association studies (GWAS) in populations and from focused studies of patients with extreme phenotypes.
人群全基因组关联研究(GWAS)和极端表型患者针对性研究均在理解动脉粥样硬化遗传理论方面取得了进步。
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