Conclusion. We suggest that a genetic variation at the IGF1R gene locus is associated with spinal disc degeneration, in line with the involvement of the IGF1R gene in the cartilage metabolism.
结论：我们认为IGF1R基因位点的遗传突变，主要是与软骨代谢相关的IGF1R基因的受累，与椎间盘退行性变有关联。
Objective to identify the disease locus in X - linked retinitis pigmentosa (XLRP) families using genetic linkage analysis.
目的应用遗传连锁分析方法对X连锁型视网膜色素变性家系进行分析，确定其致病基因的所在位点。
Objective To investigate the genetic polymorphism of HLA-B locus in Guangdong Han population and compare the characteristic of the allele frequency distribution with that in other populations.
目的调查广东汉族人群HLA-B位点基因多态性，比较不同人群HLA-B等位基因频率分布特征。
Pedigree is one of the most general population structure in the genetic linkage analysis between human single genetic inheritance disease locus and genetic marker locus.
在人类单位点致病基因与遗传标记基因的遗传连锁分析中，家系是应用得最普遍的一种群体结构。
In this study, we sought to identify functional genetic variants in the S100A14 locus and assessed their associations with susceptibility to ESCC.
本研究的目的是鉴定s100a14位点的功能性基因变异体，评价其与ESCC易感性的关系。
These approaches ignore the possibility that effects of multilocus functional genetic units play a larger role than single locus effect in determining trait variability.
这些方法忽视了多座位的功能遗传整体比单个座位对性状变化产生更大的影响。
Here we report the genetic and molecular characterization of GS3, a major quantitative trait locus for grain size.
在这里，我们报道了GS3的遗传和分子鉴定，一个主效的控制籽粒大小的数量性状基因座。
Conclusion: The results demonstrated that DYS19 locus is a good genetic marker with high determination power and can be applied to individuals identification of forensic science.
结论：DYS19基因座个人识别机率高，属较高鉴别能力的遗传标记系统，且具有明显的人群分布差异，在法医学及人类遗传学研究中具有重要的应用价值。
However, the future approaches for GWAS should be based on the multi-locus genetic model, QTN-by-environment interaction, epistatic detection and multivariate analysis.
但是，今后的方法应当是以多位点模型、环境互作、上位性检验和多个相关性状联合分析为主。
The genetic data of D7S820 locus in eight Han populations from different regions in China were collected.
收集D7S82 0基因座的8个不同地区汉族的相关遗传资料。
The genetic data of D7S820 locus in eight Han populations from different regions in China were collected.
收集D7S82 0基因座的8个不同地区汉族的相关遗传资料。
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