Scientists have discovered a breast cancer gene 30% to 40% of all breast cancers need to survive, offering what could be the biggest gene target yet for "smart bombs" to treat such tumours.
科学家们发现“30%-40%乳腺癌存活者表达乳腺癌相关基因，这些基因可能是这些患者基因靶向治疗最大的靶标”。
This gene, which has been the target of considerable research, is also known as the "warrior gene" because it regulates serotonin in the brain.
这个基因一直是相当多的研究者的目标，也被称为“尚武的基因”，因为它负责调节大脑中血清素。
If the disease is prevented or cured, the gene becomes a target for treatment.
如果这种疾病得以预防或治愈，那么这种基因便成为了治疗的对象。
The team used zinc fingers that specifically target the IPK1 gene and then added bacterial DNA that would disrupt the gene while at the same time conferring herbicide resistance to the plant.
他们团队用利用锌指结构以IPK1基因为目标，另外添加可以中断此基因同时赋予植物抗除草剂性质的细菌DNA序列。
Since humans have the same gene, the team thinks it may serve as a potential target for drugs to prevent obesity.
既然人类有一样的基因，研究小组认为研究结果有潜力去开发更有效的减肥药。
These regulate gene expression by binding to target messenger RNAs.
这些调节基因的表达和特定的信使RNA相关。
But it can take a long time for the right mutation to occur, especially if there is a very small target, like the region of DNA that controls a gene.
但要得到最合适的变异基因，耗费的时间会非常长，尤其是所要达到目标非常小时，如DNA中用来控制别的基因的区域部分，将是一项旷日持久的工程。
We used a gene therapy technique that enables us to target the brain, but ultimately there could be a pharmaceutical that enhances the signaling pathway solely in the brain.
以往我们曾经使用基因疗法，对大脑进行靶向治疗，最后我们发现可能存在一种药物，它可以单独作用于大脑，增强这条信号通路。
Trastuzumab is a humanised antibody, designed to target and block the function of HER2, a protein produced by a specific gene with cancer-causing potential.
曲妥珠单抗是一种人源化抗体，用于靶向和阻断her2的功能，而后者是由特异基因编码的一种蛋白，具有致癌潜能。
The VHL gene may be useful as a marker gene for the diagnosis of RCC and as a target gene for molecular therapy.
VHL基因可作为临床诊断指标，并可望成为肾透明细胞癌基因治疗的重要目的基因。
EGR family members are transcriptional factors that contain three repetitive zinc finger DNA binding domains which bind to EGR response elements (er) to regulate target gene expression (1).
EGR的家庭成员是包含三个重复的锌指dna结合域的转录因子，它可以EGR响应元素(ER)，调节靶基因的表达(1)。
Objective To investigate the impact of non target gene mutations and reduced permeability of the outer membrane on quinolone resistance and multiple antibiotic resistance (mar) in Escherichia coli.
目的：探讨非靶位基因突变及外膜通透性改变对大肠杆菌喹诺酮类耐药和多重耐药的影响。
To understand how LXR regulates LDLR, the authors examined transcriptional target genes of LXR and identified a gene that encodes a myosin interacting protein, IDOL.
为了了解LXR如何调节低密度脂蛋白受体，作者研究了LXR靶基因的转录，并确定了一个能编码肌球蛋白互动蛋白的基因，IDOL。
The researchers constructed the transposons in such a way that they can carry the therapeutic gene into the target cell DNA.
研究人员构建了转位子，通过转位子携带治疗基因进入靶细胞的DNA 。
SATB1 also globally regulates histone status in the chromatin by recruiting histone-modifying enzymes to the target-gene loci.
在染色体中，SATB1还在靶基因位置上通过复活组蛋白修饰酶普遍的调节组蛋白的状态。
Various chemical inducible systems based on activation and inactivation of the target gene had been described.
建立于目标基因激活和失活基础之上的几个化学分子诱导基因表达系统已有报道。
The classical mechanism for nuclear receptors to regulate gene expression is to bind the hormone response element(HRE) on the target gene in the presence of their ligands.
核受体家族的经典作用机制是在其配基存在下结合在靶基因的应答元件上，从而在转录水平上调节基因的表达。
The regulation of a target gene expression is very important in gene therapy .
在基因治疗中，实现目的基因的调控表达是非常重要的。
Application of hemopoietic stem cells included hemopoietic stem cell transplantation and as target cells for gene therapy.
造血干细胞的应用包括造血干细胞移植和作为基因治疗的靶细胞。
These key enzyme genes in the anthocyanidin synthesis pathway were research objects of flower color molecular breeding work, and F3 '5h was the target gene of blue flower breeding research.
花色素苷代谢途径中关键酶基因的研究一直是花色分子育种工作的主要研究对象，其中F 3'5 'H基因是蓝色花卉育种的研究热点。
Objective To review the advances of target gene therapy of liver cancer.
目的介绍目前关于肝癌基因治疗靶向性研究的进展。
A conditional expression model, in which the target gene is deleted in the presence of a tetracycline derivative, was used to delete the VEGF gene from podocytes.
一个有条件的表达模型用来从足突细胞中删除VEGF基因，在四环素衍生物的出现下靶基因被删除。
METHODS: We analyzed the gene sequences and protein structures of BMP-1 and its related proteins, and chose a highly conserved fragment as target gene.
方法：通过分析BMP - 1类各种分子的基因序列及蛋白结构，选择其中的一个片段作为目的基因。
Objective To investigate the effects of target gene mutations on the quinolones resistance in Escherichia coli.
目的探讨大肠埃希菌靶位基因突变对喹诺酮类药物耐药的影响。
Synthetic parameters of the PCR are very important to obtain ideal target gene.
获取理想的目的基因PCR反应的综合参数比十分重要。
The favorable peculiarity of this method is that it can demonstrate the absence of the target gene by the production of white precipitate of magnesium pyrophosphate .
该方法的一大特色是，可以通过反应副产物-白色焦磷酸镁沉淀的产生与否判断靶基因的存在。
Objective: to establish a stable cell line that can be induced to express a target gene.
目的：建立一个可诱导表达目的基因的细胞系以研究新基因的功能。
Objective: to establish a stable cell line that can be induced to express a target gene.
目的：建立一个可诱导表达目的基因的细胞系以研究新基因的功能。
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