These gene mutation distributing in all over the whole coding section of ATM gene. Every Exon exist the gene mutated site and no obvious hot mutated site be discovered.
这些突变分布于atm基因整个编码区，每个外显子都存在基因变异位点，没有发现明显的突变热点。
For example, the hereditary hemochromatosis mutation protects carriers from iron-deficiency because the mutated gene allows increased efficiency of iron absorption.
例如，因为突变的基因可以提高铁的吸收效率，所以遗传性血色素沉着病突变可以保护带菌者不缺铁。
We have to do in-vitro cell culture experiments first, prove it in an animal model, and then develop a molecule or protein which will affect the mutated gene product.
我们首先得做一个体外细胞培养实验，在动物模型中证明它的存在，然后开发出一种能影响突变基因产物的分子或蛋白质。
When mutated, the gene causes a tumor, but one that the rat's immune system can attack and destroy.
基因突变时会引发肿瘤，但是是一个老鼠的免疫系统能攻击和摧毁的。
The redhead sprang from a mutated gene in Europe thousands of years ago.
几千年前的欧洲，红头发的人因为基因变异的关系凭空出现。
They found the cancer cells of mother and baby carried the identical mutated cancer gene (called BCR-ABL1), but the infant had not inherited this gene.
他们发现母亲和婴儿的癌细胞携带有相同的突变癌基因（被称为BCR-ABL1），但是婴儿并没有得到这种基因的遗传。
The plants were derived from two Arabidopsis parents with essentially identical genomes, but with one having a mutated DDM1 DNA methylation gene.
这些植株源自两棵基因几乎相同的拟南芥，但其中一棵含有突变的DDM1甲基化DNA。
Roche's vemurafenib attacks advanced melanoma by blocking the mutated form of a gene, B-RAF.
罗氏公司的vemurafenib通过阻断一种突变的基因b - raf攻击晚期黑色素瘤。
About half of all melanoma patients have a mutated BRAF gene. This mutation tells the cell to continue to grow.
将近半数的黑色素瘤患者都有BRAF基因突变，从而导致黑色素肿瘤细胞继续生长。
One drug specifically targets a mutated gene that tells a cancer cell to grow, the other boosts a patient's immune system in the fight against the disease.
一种治疗药物以突变的基因为靶点，该基因突变后能让肿瘤细胞持续增多。另一种药物能激活病患免疫系统对抗疾病。
Researchers identified this hormone 20 years later by isolating the gene that was mutated in the obese mice.
20年后，研究者通过提取肥胖老鼠的突变基因鉴定出这一激素。
But keep in mind that the scientists say this mutated gene may be rare.
但是让人记住的是，科学家说这种突变基因可能是罕见的。
Some of the mice also had defective versions of the tumor suppressor gene p53, which is mutated in about half of human lung cancers.
一些小鼠还有肿瘤抑制基因p 53缺陷，这种缺陷突变存在与大约一半的人类肺癌。
Lupski's three sick siblings also had both of these mutations, whereas his four healthy siblings and parents (who do not have the disease) carried only one mutated gene.
鲁普斯基的三个姊妹都发生有这种变异，而他的另外四位健康的姊妹及其父母(他们都未发病)仅仅是携带变异基因。
The French team sequenced the human counterpart, UNC93B1, and found that their patient carried two mutated copies of this gene.
法国研究人员将人类的类似基因UNC93B1进行排序，发现他们的病人也携带着一对突变基因。
He could even control bone formation in the mice with the mutated gene by giving them a diet deficient in tryptophan, the precursor of serotonin.
他甚至通过喂给复合胺前体色氨酸缺乏的饲料来控制变异基因鼠的骨形成。
However, only a single copy of the gene is mutated in tumours, raising the possibility that the mutations do not result in a simple loss of function.
然而，在肿瘤中只有一个基因的单一复制出现突变，那就会增加突变的可能性而不仅仅是导致一个简单功能的丢失。
At the same time the37 year-old Fisher was also found to have the BRIP 1gene, a second mutated gene that carries its own elevated risks of both breastand ovarian cancers.
同时，现年37岁的凯莉费雪发现也带有BRIPP1的基因，第二种对于乳癌及卵巢癌有极高影响机率的突变基因。
In early 2006, they found a second, unrelated patient who had also inherited two mutated copies of the gene—although the mutation in her case was different.
2006年初，他们发现另一个与前者无关联的病人也遗传了一对突变基因—尽管她的突变与前者不同。
The research team used so-called SOD-1 rats, animals engineered to carry a mutated human gene for an inherited form of als.
这个研究小组应用的是所谓的SOD - 1鼠，被设计成携带一个遗传形成ALS的突变的人类基因。
A mutated gene has been found in a third of patients with the most common form of kidney cancer.
研究发现，约三分之一的普通肾癌患者患病与基因突变有关系。
Parents carrying the mutated gene can only have it on one of the gene pairs, the other gene being normal.
家长携带突变基因只能有它的其中一个基因对，其他基因被正常。
Genetic study indicated that the mutated green-revertible albino leaf color trait specially expressed at seedling stage was controlled by a single recessive gene.
遗传研究表明，白化转绿型突变性状受单隐性基因控制，并在幼苗阶段特异性表达。
AIM: to construct the recombinant plasmids expressing full-length HCV core protein gene and 3 different deletion mutated hepatitis core protein genes and to express them in E. coli.
目的：构建丙型肝炎病毒(HCV)全长及3种不同缺失突变的核心蛋白基因的原核表达载体，并在大肠杆菌中表达。
Their mother was a carrier of the mutated WASP gene.
其母亲为此突变WASP基因携带者。
An epigenetic event is when non-genetic factors cause a gene to change its expression, and this is different from cancer caused by mutated genes that produce errant protein.
表观遗传是指非遗传的因素(译者注：dna序列不发生改变)引起基因表达的改变，这与基因突变导致翻译出错误蛋白有明显的区别。
In the brothers, it seems the mutated RSPO1 gene could not fulfil its switching-off role, leaving SOX9 on and leading to male development.
四兄弟的突变的RSPO1基因可能失去其关闭SOX9基因的功能，所以向男性发育。
In the brothers, it seems the mutated RSPO1 gene could not fulfil its switching-off role, leaving SOX9 on and leading to male development.
四兄弟的突变的RSPO1基因可能失去其关闭SOX9基因的功能，所以向男性发育。
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