Gene chip has been an important way to detect gene changes of organism in different condition.
基因芯片技术已经成为检测不同状态下生物体基因变化的重要手段。
The references for medullary thyroid carcinoma on gene changes, diagnosis and treatment with gene in recent years are reviewed.
本文对近年来甲状腺髓样癌基因改变,诊断和治疗研究近况进行了综述。
But the most surprising finding was that the mice that only started dieting in old age also benefited from 70 per cent of these gene changes.
但是最令人吃惊的发现却是那些只是在老年时期节食的老鼠们受益于70%的基因变异。
The research, published in the American Journal of Respiratory and Critical Care Medicine, is the first study to comprehensively review gene changes in rhinovirus.
这个发表在美国呼吸和危重病学杂志上的研究,是第一个综述了鼻病毒基因改变的研究。
These technologies made it possible to study the influences of nutrients on gene and protein expression, and reversely, the influences of gene changes in nutrient related disturbances in metabolism.
通过这些技术,可以从分子水平探索营养素对基因和蛋白质表达的影响,也可以反观基因改变对营养相关性疾病发生的影响。
Others think that gene editing is still in its experimental periods and could result in terrible changes.
其他人认为基因编辑仍处于实验阶段,可能会导致可怕的变化。
And mice with the humanized gene show brain circuit changes known to be linked to human speech.
植入这种基因的老鼠在脑电波变化上显示出与人类说话时的某种相关。
Changes in gene expression may help explain why so many diets fail.
基因表达的改变可以解释为什么这么多人节食都失败了。
He added that the challenge was to next move beyond this correlative study to figure out how these gene variations may lead to functional changes that contribute to the molecular process of aging.
他补充说,挑战在于这一相关性研究的下一步,即弄清楚这些变异基因如何可能导致分子老化过程的功能性变化。
Even this short, relatively mild food reduction resulted in long-term changes in gene expression, the researchers found.
研究人员发现,即使是这种相对较轻的短期食物减少也会引起基因表达的长期改变。
Environmentally triggered alterations in genes - known as epigenetic changes - can affect when a gene is activated, how robustly it is turned on and how it interacts with neighboring genes.
环境所引发的基因变异被称为“表观遗传变化”,它可能会影响基因被激活的时间、被激活的程度以及它如何与邻近基因相互配合。
There are other examples of success in specifically targeting genetic changes in never-smokers with lung cancer, such as treatments of tumors with alterations in the EML4-ALK gene.
针对不吸烟者的基因改变进行靶向治疗,这有些其它的成功例子,比如针对有EML4-ALK基因改变的肿瘤进行的治疗。
"These changes in gene expression are likely the earliest biologic abnormalities in the small airway epithelium that lead to clinically detectable lung disease," they wrote.
他们写到,“这些基因表现度的变化貌似是诊断肺部疾病的呼吸道上皮细胞最早期生理异常改变”。
“These changes in gene expression are likely the earliest biologic abnormalities in the small airway epithelium that lead to clinically detectable lung disease,” they wrote.
他们写到,“这些基因表现度的变化貌似是诊断肺部疾病的呼吸道上皮细胞最早期生理异常改变”。
These chemical changes are now thought to include gene expression, not just suppression, as had been previously hypothesized.
这些化学变化如今被认为包括基因表达,而不是像过去假设的那样仅仅包括基因抑制。
Changes occur in gene expression in the brain's hippocampus and frontal lobe. However, the molecular mechanisms underlying these changes in gene regulation are not completely known.
大脑的海马区和额叶部分显示出基因上的变化,虽然,分子工程师标识出了这些变化,然而具体的关联还无法完全得知。
"This is the first major study that shows how small changes in one master regulator gene can cause a cascade of other metabolic effects in other genes," said lead author Tim Spector in a statement.
“这是第一个重要的研究,它解释了主宰调解员基因中微小的变化可以引发串联的其它基因的新陈代谢变化,”主作者TimSpector在声明中说。
But because the DNA code itself remained unchanged, Morris's team suggest that the changes in gene expression are epigenetic.
但由于DNA密码本身并无变化,莫里斯的团队认为这些基因表达的调整是表观的。
Although the gene is thought to cause only 1% of cases directly, the mutation is linked to changes seen in 90% of patients with the disease.
尽管这个基因只能直接造成大约1%的疾病,但是90%的患者这个基因都发生了突变。
These deletions or duplications, also called copy-number changes, can change the dosage of a gene.
这些缺失或者是重复,也被称做是拷贝数的改变,能改变一个基因的数目。
Changes in viral gene expression can have a dramatic nonlinear effect on gene networks that control whether viruses burst out of the host cell or enter a latent state.
病毒基因表达的改变对控制宿主细胞命运的基因网络具有显著的非线性作用,其可以决定细胞裂解或是进入潜伏状态。
Gene expression changes brought on by heavy smoking may persist long after the smoker has kicked the habit, researchers have found.
研究人员发现,由严重吸烟导致的基因表达改变在戒烟后会长期存在。
The changes can affect gene activity, including susceptibility to diseases.
这种变化将影响基因的活性,包括对疾病的易感性。
Previous studies had found age-related changes in gene expression in the hippocampus, a crucial memory center in the brain.
先前的研究已经发现在海马体中,存在于年龄相关变化的基因表达,海马体是大脑中的记忆中枢。
The sugar overload apparently triggered long-term changes in gene activity... which accelerated aging and had the sugar-buzzed flies dropping like, well, like flies.
糖负荷显然引发了长期的基因改变活动…这会加速老化并且会像苍蝇一样不断死去。
If the sorts of regulatory changes that underlie disease can be identified, the diseases might be treated with drugs that make a particular gene more or less active.
如果引起疾病的几种调整变化能被证实,那么就可以用药物治疗,让特定基因增加或减少活动。
If the sorts of regulatory changes that underlie disease can be identified, the diseases might be treated with drugs that make a particular gene more or less active.
如果引起疾病的几种调整变化能被证实,那么就可以用药物治疗,让特定基因增加或减少活动。
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