Methods Apraclonidine was synthesized from P-Nitraniline by reaction with reduction, adding protection group, formylation, chlorination, cyclization, off-protecting group.
方法采用对硝基苯胺为原料，经还原、加保护基、甲酰化、氯化、环合、脱保护基六步反应法可进行化学合成。
Methods Apraclonidine was synthesized from P-Nitraniline by reaction with reduction, adding protection group, formylation, chlorination, cyclization, off-protecting group.
方法采用对硝基苯胺为原料，经还原、加保护基、甲酰化、氯化、环合、脱保护基六步反应法可进行化学合成。
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