Conclusion Due to significant first pass metabolism, the drug was mainly existed in the form of glucuronidated genistein in the plasma.
结论染料木黄酮首过代谢突出，血浆中药物主要以葡糖醛酸结合形式存在。
For drugs with an active metabolite, the therapeutic consequence of first-pass metabolism depends on the contributions of the drug and the metabolite to the desired and undesired effects.
对于那些生成活性代谢物的药物来讲，经过首过代谢的治疗上的重要性取决于药物和代谢物所引起的期望的和非期望的效应。
ConclusionThe metabolism of DBDCT in rat liver microsomes was faster, suggesting that the liver first-pass effect of the drug may be stronger.
结论DBDCT在大鼠肝微粒体中代谢较快，提示该药可能肝首过效应较强。
ConclusionThe metabolism of DBDCT in rat liver microsomes was faster, suggesting that the liver first-pass effect of the drug may be stronger.
结论DBDCT在大鼠肝微粒体中代谢较快，提示该药可能肝首过效应较强。
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