Objective To investigate the relationship between hepatic fibrosis and hepatic stellate cell (HSC).
目的研究肝星状细胞(HSC)与肝纤维化和肝硬化的关系。
This paper briefly reviews the hepatic stellate cells (HSC) activation and proliferation-related signal transduction pathway and explores the role in the pathogenesis of liver fibrosis.
本综述以肝星状细胞激活与增殖相关信号转导通路为中心，探讨其在肝纤维化发病作用方面的作用机制。
Conclusion matrine can inhibit HSC proliferation and induce apoptosis of HSC, which might be one of the mechanisms of matrine to counteract liver fibrosis.
结论苦参碱可抑制HSC增殖、诱导HSC凋亡，可能是苦参碱抗肝纤维化的机制之一。
The study of HSC on the origin, distribution and phenotypic changes will provide a new direction for the treatment and reversal of hepatic fibrosis.
对HSC起源、分布与表型转变的研究将为治疗与逆转肝纤维化提供新的方向。
Recent studies show that the common pathway of liver fibrosis is mediated by HSC although various causes differ in the pathomechanism.
近年来的研究发现，尽管不同病因导致肝病的发病机制不同，但肝纤维化发生的共同途径均是HSC。
In further study we also found that such a mechanism of anti-fibrosis may be the impact on proliferation and apoptosis of MSC to HSC.
进一步研究我们还发现，这种抗肝纤维化的机制可能是MSC对HSC的增殖与凋亡发生影响。
In further study we also found that such a mechanism of anti-fibrosis may be the impact on proliferation and apoptosis of MSC to HSC.
进一步研究我们还发现，这种抗肝纤维化的机制可能是MSC对HSC的增殖与凋亡发生影响。
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